| Neurodevelopmental outcomes in infants after surgery for congenital heart disease: a comparison of single-ventricle vs. two-ventricle physiology. | |
| | |
MedLine Citation:
|
PMID: 20412480 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
INTRODUCTION: The neurodevelopmental outcome of children with repaired congenital heart defect has risen in importance with improved survival. This study compares neurodevelopmental outcomes of children who had CHD with single ventricle physiology with those who had CHD with two-ventricle physiology. PATIENTS AND METHODS: Participants included 112 infants discharged from the NICU between February 1999 to August 2006. The 12 infants who had a known genetic defect were excluded. Of the 100 infants 26 had single ventricle physiology and 74 had CHD with two-ventricle physiology. The children were seen in a follow-up clinic and growth parameters and standardized instruments were used to evaluate development. The referral rate to early intervention services was also compared. RESULTS: The number of functional ventricles did not significantly differentiate growth parameters at 6-8 months of age. Early cognitive outcomes were relatively unimpaired in both the groups (single ventricle vs. two ventricle physiology). Early motor outcomes were worse in (p < 0.05) CHD with single ventricle physiology. The rate of referral for early intervention services was high in both groups compared to the average rate of referral in the state, but there was not a significant difference between the CHD groups. CONCLUSION: Significant differences noted on motor outcomes at the 6-8 month visit were no longer apparent in later visits. Referral to early intervention services is high in both the groups. These findings are important to those caring for infants with CHD because many of these patients may need referral for early intervention. |
| | |
Authors:
|
Arvind Hoskoppal; Holly Roberts; John Kugler; Kim Duncan; Howard Needelman |
Publication Detail:
|
Type: Comparative Study; Journal Article |
Journal Detail:
|
Title: Congenital heart disease Volume: 5 ISSN: 1747-0803 ISO Abbreviation: Congenit Heart Dis Publication Date: 2010 Mar-Apr |
Date Detail:
|
Created Date: 2010-04-23 Completed Date: 2010-07-20 Revised Date: 2011-05-05 |
Medline Journal Info:
|
Nlm Unique ID: 101256510 Medline TA: Congenit Heart Dis Country: United States |
Other Details:
|
Languages: eng Pagination: 90-5 Citation Subset: IM |
Affiliation:
|
Department of Pediatrics, University of Nebraska Medical Center, Omaha, NE 68198-5380, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Child Development* Child, Preschool Cognition* Heart Defects, Congenital / complications, pathology, surgery* Heart Ventricles / abnormalities* Humans Infant Motor Skills* Neurologic Examination |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Quality of heart failure management: a comparison of care between a comprehensive heart failure prog...
Next Document: Birth weight and prematurity in infants with single ventricle physiology: pediatric heart network in...