Document Detail

Neurodevelopmental outcome in ECMO vs near-miss ECMO patients at 5 years of age.
MedLine Citation:
PMID:  10752007     Owner:  NLM     Status:  MEDLINE    
The objective of this study was to compare the outcome of children at 5 years of age who were treated with extracorporeal membrane oxygenation (ECMO) and those who were critically ill but did not meet ECMO criteria, identified as near-miss ECMO. In one of the longest studies of its kind, we compared the neurodevelopmental outcome of 76 5-year-old ECMO-treated children with 20 5-year-old near-miss ECMO patients with similar primary diagnoses. The two groups were compared for demographic data, level of ventilatory support, and degree of hyperventilation. The comprehensive assessment protocol included an assessment of intelligence (IQ), attainment of preacademic and early academic skills, and parents' report of adaptive behavior. Both groups had similar demographic data and primary diagnosis. The near-miss ECMO patients required increased ventilatory support but not significantly more than the ECMO patients. The cognitive outcome was similar in both groups with mean estimated Full-Scale IQ in the normal range for near-miss and ECMO groups (89 and 97, respectively). Rates of severe mental handicap (FSIQ < 70) (near-miss = 11%, ECMO = 12%) and risk for school failure (near-miss = 38%, ECMO = 37%) were also similar. More parents of near-miss ECMO patients reported immature adaptive skills than did parents of ECMO patients, although the numbers were small in each group. Rates of parent-reported child behavior problems were similar in both groups. ECMO and near-miss ECMO patients have similar cognitive and adaptive outcomes at 5 years of age. A significant number in each group are at risk of school failure and should be closely followed up.
K Rais-Bahrami; A E Wagner; C Coffman; P Glass; B L Short
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Clinical pediatrics     Volume:  39     ISSN:  0009-9228     ISO Abbreviation:  Clin Pediatr (Phila)     Publication Date:  2000 Mar 
Date Detail:
Created Date:  2000-06-20     Completed Date:  2000-06-20     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0372606     Medline TA:  Clin Pediatr (Phila)     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  145-52     Citation Subset:  AIM; IM    
Department of Neonatology, George Washington University School of Medicine, Washington, DC, USA.
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MeSH Terms
Central Nervous System Diseases / etiology
Child Behavior Disorders / etiology
Child, Preschool
Developmental Disabilities / etiology*
Extracorporeal Membrane Oxygenation / adverse effects*
Follow-Up Studies
Infant, Newborn
Intelligence Tests
Respiration, Artificial
Respiratory Insufficiency / therapy*
Risk Factors
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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