Document Detail

Neurodevelopmental implications of ocular motor apraxia.
MedLine Citation:
PMID:  16288671     Owner:  NLM     Status:  MEDLINE    
Ocular motor apraxia (OMA), a disorder of saccadic initiation, may be congenital or acquired. While the acquired form is frequently associated with significant neuropathology, the congenital form is often regarded as relatively benign. Many children with congenital OMA who were observed clinically have shown neurodevelopmental disturbance over time. A retrospective review was taken of 34 consecutive patients (22 males and 12 females), seen over a 20-year period, to evaluate the frequency and type of associated neurodevelopmental problems. Age at presentation ranged from 8 weeks to 14 years, with a mean age of 10 years. Of 29 children with congenital OMA, 15 had imaging evidence of structural central nervous system abnormalities (with cerebellar hypoplasia the most frequent abnormality detected). Eleven of the 14 patients with no structural abnormality showed abnormal neurodevelopment. This study suggests that congenital OMA is not a benign diagnosis, even in the absence of overt neurological disturbance at the time of presentation.
J E Marr; S H Green; H E Willshaw
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Developmental medicine and child neurology     Volume:  47     ISSN:  0012-1622     ISO Abbreviation:  Dev Med Child Neurol     Publication Date:  2005 Dec 
Date Detail:
Created Date:  2005-11-18     Completed Date:  2005-12-23     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0006761     Medline TA:  Dev Med Child Neurol     Country:  England    
Other Details:
Languages:  eng     Pagination:  815-9     Citation Subset:  IM    
Hallamshire Hospital, Sheffield, UK.
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MeSH Terms
Age of Onset
Child Development
Child, Preschool
Nervous System / growth & development*
Ocular Motility Disorders / complications*,  congenital*
Retrospective Studies
Risk Factors

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