Document Detail

Neurodevelopmental outcome following congenital cytomegalovirus infection in preterm infants with twin-to-twin transfusion syndrome: a case report.
MedLine Citation:
PMID:  20806166     Owner:  NLM     Status:  MEDLINE    
Twin-to-twin transfusion syndrome and conital cytomegalovirus infection bear the risk of brain damage. In the 27th week of gestation of a twin pregnancy a Caesarean section was performed because of pathological cardiotocogram and Doppler ultrasonography of the second twin (recipient). Both infants presented with severe, persistent thrombocytopenia, elevated liver enzymes and direct hyperbilirubinemia. Primary congenital CMV infection was diagnosed. Both twins showed severe neuropathological symptoms, pathological aEEG with seizure activity and severe neurodevelopmental delay at corrected age of 12 months. The severity of brain pathology, the complex etiology, its consequence for neurotion with extreme prematurity make this case of special interest.
E Griesmaier; V Neubauer; S Blum; R Trawöger; M Keller; U Kiechl-Kohlendorfer
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2010-08-30
Journal Detail:
Title:  Klinische Pädiatrie     Volume:  222     ISSN:  1439-3824     ISO Abbreviation:  Klin Padiatr     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-08-31     Completed Date:  2011-01-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0326144     Medline TA:  Klin Padiatr     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  312-4     Citation Subset:  IM    
Copyright Information:
Georg Thieme Verlag KG Stuttgart, New York.
Innsbruck Medical University, Department of Pediatrics IV, Innsbruck, Austria.
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MeSH Terms
Brain Damage, Chronic / diagnosis
Central Nervous System Cysts / diagnosis
Cytomegalovirus Infections / congenital*,  diagnosis*
Developmental Disabilities / diagnosis*
Diseases in Twins / diagnosis*
Fetofetal Transfusion / diagnosis*
Follow-Up Studies
Gastroschisis / diagnosis
Infant, Newborn
Infant, Premature, Diseases / diagnosis*
Magnetic Resonance Imaging
Polymerase Chain Reaction
Respiratory Distress Syndrome, Newborn / diagnosis
Retinopathy of Prematurity / diagnosis
Spasms, Infantile / diagnosis

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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