| Neurodevelopment and neurodegeneration: are there critical stages for nutritional intervention? | |
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MedLine Citation:
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PMID: 20946370 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Rather than being an inevitable consequence of age, cognitive decline can occur with marked variation among individuals. In this context, nutrition is one factor that is believed to be influential. When considering the potential role of diet, two factors need to be considered. First, cognitive or brain reserve is said to decrease the incidence of dementia; that is, it has been suggested that those with larger brains and better intellectual functioning have a greater capacity to resist the effects of the biological changes that define dementia. As such, the adequacy of nutrition before birth and in the early formative years may have long-term consequences. Second, shrinkage of the brain begins in young adulthood, suggesting that any insidious influence of diet will take place from that time onward over a period of many decades. The marked decline in the weight of the brain associated with advanced dementia suggests it will be easier to slow that decline than to repair the brain. If this model is accurate, diet is influential throughout the entire lifespan, and this has substantial methodological implications for the study of the topic. |
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Authors:
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David Benton |
Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Nutrition reviews Volume: 68 Suppl 1 ISSN: 1753-4887 ISO Abbreviation: Nutr. Rev. Publication Date: 2010 Nov |
Date Detail:
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Created Date: 2010-10-15 Completed Date: 2010-12-10 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0376405 Medline TA: Nutr Rev Country: United States |
Other Details:
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Languages: eng Pagination: S6-10 Citation Subset: IM |
Copyright Information:
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© 2010 ILSI Europe. |
Affiliation:
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Department of Psychology, University of Swansea, Wales, United Kingdom. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Aged, 80 and over Aging / physiology* Brain / growth & development, physiology* Child Child, Preschool Dementia / prevention & control Diet Female Humans Infant Infant, Newborn Male Middle Aged Nervous System Physiological Phenomena* Neuronal Plasticity Nutritional Physiological Phenomena / physiology* Pregnancy Prenatal Nutritional Physiological Phenomena / physiology Young Adult |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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