Document Detail


Neurocysticercosis. Short course of treatment with albendazole.
MedLine Citation:
PMID:  2818259     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Eighteen patients with nonenhancing parenchymal brain cysts were treated with albendazole; 9 patients were treated for 3 days and 9 patients for 1 month at daily doses of 15 mg/kg of body weight. Three months after starting therapy, results showed that in both groups the treatment was highly effective. Control studies carried out in the same group before the trial did not show any significant improvement. Five patients were controls and were treated only with symptomatic drugs. The total diameter of the lesions was reduced from 220.1 mm to 52.1 mm, which signifies a reduction of 76.3% in patients treated for a period of 3 days, and from 278.5 mm to 82.1 mm, which is 70.5%, in patients treated for 30 days. We conclude that albendazole administered according to the 3-day therapeutic scheme proposed above is as highly effective for the treatment of parenchymal brain cysticercosis as the 30-day scheme.
Authors:
F Alarcón; L Escalante; G Dueñas; M Montalvo; M Román
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Archives of neurology     Volume:  46     ISSN:  0003-9942     ISO Abbreviation:  Arch. Neurol.     Publication Date:  1989 Nov 
Date Detail:
Created Date:  1989-12-12     Completed Date:  1989-12-12     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372436     Medline TA:  Arch Neurol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1231-6     Citation Subset:  AIM; IM    
Affiliation:
Department of Neurology, Eugenio Espejo Hospital, Quito, Ecuador.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Albendazole / therapeutic use*
Brain Diseases / cerebrospinal fluid,  drug therapy*,  radiography
Cysticercosis / cerebrospinal fluid,  drug therapy*,  radiography
Female
Humans
Male
Middle Aged
Tomography, X-Ray Computed
Chemical
Reg. No./Substance:
54965-21-8/Albendazole
Comments/Corrections
Comment In:
Arch Neurol. 1990 Dec;47(12):1278-9   [PMID:  2252445 ]
Arch Neurol. 1990 Oct;47(10):1059-60   [PMID:  2222234 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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