| Neurocognitive impairment and psychiatric comorbidity in well-controlled human immunodeficiency virus-infected Thais from the 2NN Cohort Study. | |
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MedLine Citation:
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PMID: 20053142 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This research is a cross-sectional study to determine the frequency of neurocognitive impairment and psychiatric comorbidity among Thais maintained on highly active antiretroviral therapy (HAART) with undetectable plasma human immunodeficiency virus (HIV) RNA in the 2NN Cohort. Sixty-four subjects were evaluated with neurological examinations, neuropsychological testing, and psychiatric questionnaires. Twenty-four subjects (37.5%) were found to have neurocognitive impairment, with 13 (20.3%), 10 (15.6%), and 1 (1.6%) classified as asymptomatic neurocognitive disorder (ANI), mild neurocognitive disorder (MND), and HIV-associated dementia (HAD), respectively. Three subjects (4.7%) had depression and no cases had significant symptoms of anxiety. A notable proportion of well-controlled individuals exhibited neurocognitive impairment. Anxiety and depression were uncommon. |
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Authors:
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Wadchara Pumpradit; Jintanat Ananworanich; Sermsak Lolak; Cecilia Shikuma; Robert Paul; Umaporn Siangphoe; Nithima Chaoniti; Peeraporn Kaew-On; Robert Paris; Kiat Ruxrungtham; Victor Valcour; |
Publication Detail:
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Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of neurovirology Volume: 16 ISSN: 1538-2443 ISO Abbreviation: J. Neurovirol. Publication Date: 2010 Feb |
Date Detail:
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Created Date: 2010-03-03 Completed Date: 2010-06-01 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9508123 Medline TA: J Neurovirol Country: England |
Other Details:
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Languages: eng Pagination: 76-82 Citation Subset: IM |
Affiliation:
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HIV-NAT, the Thai Red Cross AIDS Research Center, Bangkok, Thailand. wadchara@path.org |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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AIDS Dementia Complex
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drug therapy,
epidemiology*,
virology Adult Antiretroviral Therapy, Highly Active Anxiety / epidemiology Cognition Disorders / epidemiology* Cohort Studies Comorbidity Cross-Sectional Studies Depression / epidemiology Female HIV Humans Male Middle Aged Neuropsychological Tests Questionnaires Thailand / epidemiology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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