Document Detail


Neuroblastoma presenting with the nephrotic syndrome.
MedLine Citation:
PMID:  490283     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A case of neuroblastoma in a 4-yr-old boy presenting with the nephrotic syndrome is reported. Nether thrombosis nor stenosis of the renal veins and the inferior vena cava was present. Electron microscopy revealed lumps of subepithelial deposits as well as thickening and tortuosity of the glomerular basement membrane compatible with membranous nephropathy. It is postulated that deposition of neuroblastoma-associated immune complexes on the glomerular basement membrane-was responsible for the development of the nephrotic syndrome in this patient. Five pediatric cases of nephrotic syndrome associated with extrarenal neoplasia were collected from the world literature and are briefly discussed.
Authors:
H L Zheng; T Maruyama; S Matsuda; K Satomura
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of pediatric surgery     Volume:  14     ISSN:  0022-3468     ISO Abbreviation:  J. Pediatr. Surg.     Publication Date:  1979 Aug 
Date Detail:
Created Date:  1979-12-29     Completed Date:  1979-12-29     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0052631     Medline TA:  J Pediatr Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  414-9     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Child, Preschool
Humans
Male
Nephrotic Syndrome / etiology*,  pathology,  radiography
Neuroblastoma / complications*,  pathology,  radiography
Retroperitoneal Neoplasms / complications*,  pathology,  radiography

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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