Document Detail

Neuroblastoma-like schwannoma of lumbar spinal nerve root.
MedLine Citation:
PMID:  20594022     Owner:  NLM     Status:  MEDLINE    
Neuroblastoma-like schwannoma is a rare nerve sheath tumor with histological features resembling a neuroblastoma. A comprehensive literature review identified only 10 previous case reports of this condition. The authors present the first reported case of a neuroblastoma-like schwannoma at a spinal nerve root. The patient, a 61-year-old woman, presented with severe pain in the right lower extremity that failed to resolve after conservative management. Magnetic resonance imaging revealed an intradural enhancing lesion extending out of the right neural foramen at L1-2. A right L1-2 hemilaminectomy and facetectomy with gross-total resection of the tumor was performed without complications. Neuroblastoma-like schwannoma was diagnosed based on histopathological examination of the biopsied tumor specimen. A postoperative course of serial examination and imaging was chosen based on a suspected benign postoperative course as in the case of a completely resected schwannoma. The authors present the novel case of neuroblastoma-like schwannoma at a lumbar spinal nerve root and describe the distinguishing pathological features of this rare lesion.
Giriraj K Sharma; Jennifer M Eschbacher; Timothy D Uschold; Nicholas Theodore
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of neurosurgery. Spine     Volume:  13     ISSN:  1547-5646     ISO Abbreviation:  J Neurosurg Spine     Publication Date:  2010 Jul 
Date Detail:
Created Date:  2010-07-02     Completed Date:  2010-08-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101223545     Medline TA:  J Neurosurg Spine     Country:  United States    
Other Details:
Languages:  eng     Pagination:  82-6     Citation Subset:  IM    
Divisions of Neurological Surgery, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, Arizona, USA.
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MeSH Terms
Diagnosis, Differential
Laminectomy / methods
Lumbar Vertebrae / innervation*
Magnetic Resonance Imaging
Middle Aged
Neurilemmoma / diagnosis*,  pathology,  surgery
Neuroblastoma / diagnosis*,  pathology,  surgery
Spinal Cord Neoplasms / diagnosis*,  pathology,  surgery
Spinal Nerve Roots / pathology*

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