Document Detail

Neuroblastoma: diagnostic imaging and staging.
MedLine Citation:
PMID:  6856817     Owner:  NLM     Status:  MEDLINE    
Results of computed tomography (CT), scintigraphy, excretory urography, and other imaging tests used to diagnose and stage 38 cases of neuroblastoma prior to treatment were reviewed. Findings of these examinations were correlated with clinical data, laboratory data, results of biopsy, and surgical findings. CT was the most sensitive single test (100%) for the detection and delineation of the primary tumor. Calcifications that suggested the histologic diagnosis of neuroblastoma were present in 79% of the cases. Rim calcifications, the most specific pattern for neuroblastoma, were identified in 29% of all cases. CT alone accurately staged 82% of cases; when complemented by bone marrow biopsy, staging accuracy was 97%. CT alone was more accurate than any combination of imaging tests that excluded CT. An algorithm using CT is presented for the diagnosis and staging of neuroblastoma at reduced cost and with increased efficiency.
D D Stark; A A Moss; R C Brasch; A A deLorimier; A R Albin; D A London; C A Gooding
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Radiology     Volume:  148     ISSN:  0033-8419     ISO Abbreviation:  Radiology     Publication Date:  1983 Jul 
Date Detail:
Created Date:  1983-07-15     Completed Date:  1983-07-15     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0401260     Medline TA:  Radiology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  101-5     Citation Subset:  AIM; IM    
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MeSH Terms
Bone Marrow / pathology
Bone Neoplasms / radiography,  radionuclide imaging,  secondary
Follow-Up Studies
Liver Neoplasms / radiography,  secondary
Neoplasm Staging / methods*
Neuroblastoma / pathology,  radiography*,  radionuclide imaging
Tomography, X-Ray Computed* / economics
Grant Support

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