Document Detail

Neurobiology of zinc-influenced eating behavior.
MedLine Citation:
PMID:  10801965     Owner:  NLM     Status:  MEDLINE    
Zinc is an essential nutrient that is required in humans and animals for many physiological functions, including immune and antioxidant function, growth and reproduction. Many aspects of zinc deficiency-induced anorexia have been well studied in experimental animals, most notably the laboratory rat. There is evidence that suggests zinc deficiency may be intimately involved with anorexia in humans: if not as an initiating cause, then as an accelerating or exacerbating factor that may deepen the pathology of the anorexia. The present review describes recent research investigating the relationship between zinc deficiency and the regulation of food intake, along with advances in the understanding of the food intake and body weight regulation systems. For more comprehensive reviews of zinc nutrition and zinc deficiency, readers are referred to the other reviews in this volume and the review text of Mills (1989). An excellent review focused solely on zinc status and food intake has been presented by O'Dell and Reeves (1989).
N F Shay; H F Mangian
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.; Review    
Journal Detail:
Title:  The Journal of nutrition     Volume:  130     ISSN:  0022-3166     ISO Abbreviation:  J. Nutr.     Publication Date:  2000 May 
Date Detail:
Created Date:  2000-06-08     Completed Date:  2000-06-08     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0404243     Medline TA:  J Nutr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1493S-9S     Citation Subset:  IM    
Department of Biological Sciences, University of Notre Dame, Notre Dame, IN 46556, USA.
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MeSH Terms
Anorexia / etiology
Appetite Regulation / physiology*
Feeding Behavior / drug effects*
Galanin / physiology
Leptin / physiology
Neuropeptide Y / physiology
Zinc / deficiency*,  pharmacology,  physiology
Grant Support
Reg. No./Substance:
0/Leptin; 0/Neuropeptide Y; 7440-66-6/Zinc; 88813-36-9/Galanin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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