| Neurobiology of language recovery after stroke: lessons from neuroimaging studies. | |
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MedLine Citation:
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PMID: 22202187 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Saur D, Hartwigsen G. Neurobiology of language recovery after stroke: lessons from neuroimaging studies. Language is organized in large-scale, predominantly left-lateralized, temporo-parieto-frontal networks in the human brain. After focal brain damage (eg, ischemic stroke), this network organization enables the brain to adaptively reorganize language functions in order to compensate lesion effects. Here, we summarize how structural and functional neuroimaging methods contribute to the current understanding of loss and recovery of language functions after stroke. This includes voxelwise lesion-behavior mapping, functional imaging for mapping reorganizational mechanisms from acute to chronic stroke, as well as imaging based outcome prediction. The review is complemented by an introductory section on language organization in the healthy brain. |
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Authors:
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Dorothee Saur; Gesa Hartwigsen |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Archives of physical medicine and rehabilitation Volume: 93 ISSN: 1532-821X ISO Abbreviation: Arch Phys Med Rehabil Publication Date: 2012 Jan |
Date Detail:
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Created Date: 2011-12-28 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 2985158R Medline TA: Arch Phys Med Rehabil Country: United States |
Other Details:
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Languages: eng Pagination: S15-25 Citation Subset: AIM; IM |
Copyright Information:
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Copyright © 2012 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved. |
Affiliation:
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Language and Aphasia Laboratory, Department of Neurology, University of Leipzig, Leipzig, Germany. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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