Document Detail

The neurobiological underpinnings of obesity and binge eating: a rationale for adopting the food addiction model.
MedLine Citation:
PMID:  23098895     Owner:  NLM     Status:  MEDLINE    
The food addiction model of overeating has been proposed to help explain the widespread advancement of obesity over the last 30 years. Parallels in neural substrates and neurochemistry, as well as corresponding motivational and behavioral traits, are increasingly coming to light; however, there are still key differences between the two disorders that must be acknowledged. We critically examine these common and divergent characteristics using the theoretical framework of prominent drug addiction models, investigating the neurobiological underpinnings of both behaviors in an attempt to justify whether classification of obesity and binge eating as an addictive disorder is merited.
Dana G Smith; Trevor W Robbins
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review     Date:  2012-10-23
Journal Detail:
Title:  Biological psychiatry     Volume:  73     ISSN:  1873-2402     ISO Abbreviation:  Biol. Psychiatry     Publication Date:  2013 May 
Date Detail:
Created Date:  2013-04-16     Completed Date:  2013-10-21     Revised Date:  2014-03-25    
Medline Journal Info:
Nlm Unique ID:  0213264     Medline TA:  Biol Psychiatry     Country:  United States    
Other Details:
Languages:  eng     Pagination:  804-10     Citation Subset:  IM    
Copyright Information:
Copyright © 2013 Society of Biological Psychiatry. Published by Elsevier Inc. All rights reserved.
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MeSH Terms
Behavior, Addictive / physiopathology*
Binge-Eating Disorder / physiopathology*
Brain / physiopathology*
Bulimia / physiopathology*
Models, Neurological
Neural Pathways / physiopathology
Obesity / physiopathology*
Grant Support
G00001354//Wellcome Trust; //Medical Research Council
Comment In:
Biol Psychiatry. 2013 Oct 1;74(7):e11   [PMID:  23726509 ]

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