Document Detail


Neurobehavioral effects from exposure to dental amalgam Hg(o): new distinctions between recent exposure and Hg body burden.
MedLine Citation:
PMID:  9707169     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Potential toxicity from exposure to mercury vapor (Hg(o)) from dental amalgam fillings is the subject of current public health debate in many countries. We evaluated potential central nervous system (CNS) toxicity associated with handling Hg-containing amalgam materials among dental personnel with very low levels of Hg(o) exposure (i.e., urinary Hg <4 microg/l), applying a neurobehavioral test battery to evaluate CNS functions in relation to both recent exposure and Hg body burden. New distinctions between subtle preclinical effects on symptoms, mood, motor function, and cognition were found associated with Hg body burden as compared with those associated with recent exposure. The pattern of results, comparable to findings previously reported among subjects with urinary Hg >50 microg/l, presents convincing new evidence of adverse behavioral effects associated with low Hg(o) exposures within the range of that received by the general population.
Authors:
D Echeverria; H V Aposhian; J S Woods; N J Heyer; M M Aposhian; A C Bittner; R K Mahurin; M Cianciola
Related Documents :
2301689 - Modified criteria for the objective diagnosis of chronic compartment syndrome of the leg.
8331609 - Balloon dilation of congenital subaortic stenosis in the dog.
6624679 - Noninvasive determination of systolic, diastolic and end-systolic blood pressure in neo...
23474659 - Assessment of left ventricular function by pulse wave analysis in critically ill patients.
8135419 - Hydrodynamic evaluation of intravenous infusion systems.
6679859 - Effects of increased systemic blood pressure on the tissue fluid pressure threshold of ...
23031149 - Dilemmas in treating hypertension in octogenarians.
15616399 - Ventilator strategies for posttraumatic acute respiratory distress syndrome: airway pre...
9559609 - Increasing tidal volumes and pulmonary overdistention adversely affect pulmonary vascul...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  FASEB journal : official publication of the Federation of American Societies for Experimental Biology     Volume:  12     ISSN:  0892-6638     ISO Abbreviation:  FASEB J.     Publication Date:  1998 Aug 
Date Detail:
Created Date:  1998-09-02     Completed Date:  1998-09-02     Revised Date:  2012-02-15    
Medline Journal Info:
Nlm Unique ID:  8804484     Medline TA:  FASEB J     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  971-80     Citation Subset:  IM    
Affiliation:
Battelle Centers for Public Health Research and Evaluation, Seattle, Washington 98105, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Affect
Brain / drug effects*
Cognition
Dental Amalgam / adverse effects*
Dental Assistants*
Dentists*
Female
Humans
Male
Mercury / adverse effects*,  urine
Middle Aged
Motor Activity
Occupational Exposure / adverse effects*
Grant Support
ID/Acronym/Agency:
DE11712/DE/NIDCR NIH HHS; ES04696/ES/NIEHS NIH HHS; ES04940/ES/NIEHS NIH HHS
Chemical
Reg. No./Substance:
7439-97-6/Mercury; 8049-85-2/Dental Amalgam

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Wound reepithelialization activates a growth factor-responsive enhancer in migrating keratinocytes.
Next Document:  Mechanics, energetics, and crossbridge kinetics of rabbit diaphragm during congestive heart failure.