Document Detail

Neurobehavioral effects from exposure to dental amalgam Hg(o): new distinctions between recent exposure and Hg body burden.
MedLine Citation:
PMID:  9707169     Owner:  NLM     Status:  MEDLINE    
Potential toxicity from exposure to mercury vapor (Hg(o)) from dental amalgam fillings is the subject of current public health debate in many countries. We evaluated potential central nervous system (CNS) toxicity associated with handling Hg-containing amalgam materials among dental personnel with very low levels of Hg(o) exposure (i.e., urinary Hg <4 microg/l), applying a neurobehavioral test battery to evaluate CNS functions in relation to both recent exposure and Hg body burden. New distinctions between subtle preclinical effects on symptoms, mood, motor function, and cognition were found associated with Hg body burden as compared with those associated with recent exposure. The pattern of results, comparable to findings previously reported among subjects with urinary Hg >50 microg/l, presents convincing new evidence of adverse behavioral effects associated with low Hg(o) exposures within the range of that received by the general population.
D Echeverria; H V Aposhian; J S Woods; N J Heyer; M M Aposhian; A C Bittner; R K Mahurin; M Cianciola
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  FASEB journal : official publication of the Federation of American Societies for Experimental Biology     Volume:  12     ISSN:  0892-6638     ISO Abbreviation:  FASEB J.     Publication Date:  1998 Aug 
Date Detail:
Created Date:  1998-09-02     Completed Date:  1998-09-02     Revised Date:  2012-02-15    
Medline Journal Info:
Nlm Unique ID:  8804484     Medline TA:  FASEB J     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  971-80     Citation Subset:  IM    
Battelle Centers for Public Health Research and Evaluation, Seattle, Washington 98105, USA.
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MeSH Terms
Brain / drug effects*
Dental Amalgam / adverse effects*
Dental Assistants*
Mercury / adverse effects*,  urine
Middle Aged
Motor Activity
Occupational Exposure / adverse effects*
Grant Support
Reg. No./Substance:
7439-97-6/Mercury; 8049-85-2/Dental Amalgam

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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