Document Detail

Neurobehavioral changes following caudate infarct: a case report with literature review.
MedLine Citation:
PMID:  1848149     Owner:  NLM     Status:  MEDLINE    
A case of left caudate infarct with its associated neurobehavioral changes is reported with review of literature. The patient showed apathy, decreased problem solving ability, impaired memory and abstract thinking, especially the verbal memory. Such behavioral and cognitive changes correspond to disturbances of specific prefrontal-caudate circuits, either dorsolateral prefrontal or lateral orbitofrontal circuits. From review of literature, it is known that patients with dorsolateral caudate involvement may show apathy, reduced spontaneity and initiative; Patients with ventromedial caudate involvement will exhibit disinhibition, disorganization and impulsiveness, and patients with larger caudate lesion may show affective symptoms with psychotic features.
P Y Wang
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Zhonghua yi xue za zhi = Chinese medical journal; Free China ed     Volume:  47     ISSN:  0578-1337     ISO Abbreviation:  Zhonghua Yi Xue Za Zhi (Taipei)     Publication Date:  1991 Mar 
Date Detail:
Created Date:  1991-04-16     Completed Date:  1991-04-16     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0005327     Medline TA:  Zhonghua Yi Xue Za Zhi (Taipei)     Country:  TAIWAN    
Other Details:
Languages:  eng     Pagination:  199-203     Citation Subset:  IM    
Department of Internal Medicine, Veterans General Hospital, Taichung, Taiwan, R.O.C.
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MeSH Terms
Brain / radiography
Caudate Nucleus / blood supply*
Cerebral Infarction / physiopathology,  psychology*
Tomography, X-Ray Computed

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