Document Detail

Neuro-ophthalmology of subacute sclerosing panencephalitis: two cases and a review of the literature.
MedLine Citation:
PMID:  23047165     Owner:  NLM     Status:  In-Data-Review    
PURPOSE OF REVIEW: To review the literature on early visual manifestations of subacute sclerosing panencephalitis (SSPE) with regard to two patients who had visual problems preceding the onset of neurological symptoms. One patient had cortical visual disturbances and the other had visual loss due to retinal pigment epithelial changes.
RECENT FINDINGS: SSPE is a chronic encephalitis characterized by a history of measles infection and a progressive disease of the central nervous system that still occurs frequently in countries with insufficient measles immunization. Visual manifestations can occur as a result of involvement of the pathways that lead from the retina to the occipital cortex during the course of the disease, but are rare as a presenting sign. Fundus changes, especially macular retinitis and macular pigment disturbances, appear to be the most common ocular manifestations of SSPE.
SUMMARY: Ophthalmologists must be aware that SSPE can knock their door with ocular findings of SSPE, months or years before the onset of neurological symptoms.
Ayse I Colpak; Sefik E Erdener; Burce Ozgen; Banu Anlar; Tulay Kansu
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Current opinion in ophthalmology     Volume:  23     ISSN:  1531-7021     ISO Abbreviation:  Curr Opin Ophthalmol     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-10-10     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9011108     Medline TA:  Curr Opin Ophthalmol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  466-71     Citation Subset:  IM    
aNeuro-Ophthalmology Unit, Institute of Neurological Sciences and Psychiatry bDepartment of Radiology cDepartment of Pediatric Neurology, Faculty of Medicine, Hacettepe University, Ankara, Turkey.
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