Document Detail

Neuro-ophthalmological findings in relation to CNS lesions in patients with myelomeningocele.
MedLine Citation:
PMID:  2354755     Owner:  NLM     Status:  MEDLINE    
Twenty-eight patients (14 male, 14 female; aged four to 34 years) with myelomeningocele were studied. Magnetic resonance imaging was used to determine the correlation between disturbances of ocular motility and the degree of hydrocephalus, tectal plate deformity and dislocation of the cerebellum and medulla oblongata. All patients had Chiari malformations. Strabismus and spontaneous nystagmus were strongly related mainly to the degree of hydrocephalus and to some extent to the amount of lower brainstem deformities. Ocular motility defects with regard to oblique muscle functions and horizontal and vertical gaze and saccadic control often correlated with lower brainstem lesions. Convergence defects correlated with deformities of the upper brainstem. However, these correlations were not valid in the individual patient; some had no strabismus and normal ocular motility, in spite of advanced hydrocephalus and Chiari malformations.
G Lennerstrand; J E Gallo; L Samuelsson
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Developmental medicine and child neurology     Volume:  32     ISSN:  0012-1622     ISO Abbreviation:  Dev Med Child Neurol     Publication Date:  1990 May 
Date Detail:
Created Date:  1990-07-24     Completed Date:  1990-07-24     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0006761     Medline TA:  Dev Med Child Neurol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  423-31     Citation Subset:  IM    
Department of Ophthalmology, Karolinska Institute, Huddinge University Hospital, Sweden.
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MeSH Terms
Arnold-Chiari Malformation / complications*,  surgery
Brain Stem / pathology
Cerebellum / pathology
Cerebrospinal Fluid Shunts
Child, Preschool
Hydrocephalus / complications*,  surgery
Magnetic Resonance Imaging
Meningomyelocele / complications*,  surgery
Nystagmus, Pathologic / etiology*
Ophthalmoplegia / etiology*
Postoperative Complications / etiology
Vision Disorders / etiology*
Comment In:
Dev Med Child Neurol. 1990 Oct;32(10):929   [PMID:  2257993 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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