| Neurite outgrowth elicited by embryonic chick heart: partial purification of the active factor. | |
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MedLine Citation:
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PMID: 530494 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Chick heart explants stimulate a dense outgrowth of neurites in co-cultured spinal, sympathetic and ciliary ganglia. A factor sharing these properties was partially purified by gel filtration of extract prepared from lyophilized 18-day embryonic hearts. The active factor has an apparent molecular weight of roughly 40,000 and is evidently distinct from nerve growth factor (NGF) by stimulating the parasympathetic ciliary neurons and by lack of cross-reactivity with antibodies to NGF. |
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Authors:
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T Ebendal; M Belew; C O Jacobson; J Porath |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Neuroscience letters Volume: 14 ISSN: 0304-3940 ISO Abbreviation: Neurosci. Lett. Publication Date: 1979 Sep |
Date Detail:
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Created Date: 1980-04-23 Completed Date: 1980-04-23 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7600130 Medline TA: Neurosci Lett Country: NETHERLANDS |
Other Details:
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Languages: eng Pagination: 91-5 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Biological Assay Chick Embryo Chromatography, Gel Ganglia / drug effects* Ganglia, Parasympathetic / drug effects Ganglia, Spinal / drug effects Ganglia, Sympathetic / drug effects Heart / embryology* Molecular Weight Nerve Growth Factors / isolation & purification*, pharmacology Stimulation, Chemical Subcellular Fractions / analysis |
| Chemical | |
Reg. No./Substance:
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0/Nerve Growth Factors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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