Document Detail


Neural tube closure: the curious case of shrinking junctions.
MedLine Citation:
PMID:  22835793     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Your brain and spinal cord began as a flat sheet, which narrowed, elongated, and rolled up to form a tube. A new study identifies a key molecular link underlying vertebrate neural tube formation, connecting planar cell polarity patterning to contraction of specific cell-cell junctions.
Authors:
Jessica Sullivan-Brown; Bob Goldstein
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Current biology : CB     Volume:  22     ISSN:  1879-0445     ISO Abbreviation:  Curr. Biol.     Publication Date:  2012 Jul 
Date Detail:
Created Date:  2012-07-27     Completed Date:  2012-11-30     Revised Date:  2013-07-15    
Medline Journal Info:
Nlm Unique ID:  9107782     Medline TA:  Curr Biol     Country:  England    
Other Details:
Languages:  eng     Pagination:  R574-6     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 Elsevier Ltd. All rights reserved.
Affiliation:
Biology Department, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. sullivjl@live.unc.edu
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MeSH Terms
Descriptor/Qualifier:
Actins / metabolism
Adherens Junctions / metabolism
Animals
Cell Polarity*
Chick Embryo / metabolism
Chickens
Humans
Myosins / metabolism
Neural Plate / cytology,  metabolism*
Neural Tube / cytology,  metabolism*
Neural Tube Defects / embryology*
Neurogenesis*
Grant Support
ID/Acronym/Agency:
R01 GM083071/GM/NIGMS NIH HHS
Chemical
Reg. No./Substance:
0/Actins; EC 3.6.4.1/Myosins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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