Document Detail


Neural substrates of cognitive load changes during a motor task in subjects with stroke.
MedLine Citation:
PMID:  18978666     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: A critical component to rehabilitation is the degree to which we challenge patients to facilitate learning without providing excessive competition for cognitive resources. The purpose of this study was to examine brain activation and motor performance during changes in cognitive load in a continuous motor task in subjects with stroke (n = 7) and healthy subjects (n = 17). METHODS: Subjects participated in a joystick drawing task during functional magnetic resonance imaging. Subjects attempted to continuously draw a square under three conditions of varying cognitive demands. RESULTS: In subjects with stroke, results showed significantly less activation in contralateral primary motor area when the task did not require working memory demands and no change when the condition required online visual feedback processing. Bilaterally, the premotor cortex also demonstrated a significant decrease in activation when the task did not require working memory and then an increase in activation when online visual feedback processing was required. Despite these changes in activation, the accuracy of performance was maintained across the three conditions. Healthy subjects demonstrated no significant differences in activation between conditions. CONCLUSION: These data suggest that the sensorimotor areas investigated have the greatest demand when the task requires working memory, but that only the bilateral premotor area has increased demands when online visual feedback processing is required. Use of working memory and visual feedback should be carefully considered when designing rehabilitation programs to balance challenging patients with overwhelming their potentially limited cognitive resources.
Authors:
Teresa Jacobson Kimberley; Scott M Lewis; Carolyn Strand; Brooke Darst Rice; Stephanie Hall; Patricia Slivnik
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of neurologic physical therapy : JNPT     Volume:  32     ISSN:  1557-0576     ISO Abbreviation:  J Neurol Phys Ther     Publication Date:  2008 Sep 
Date Detail:
Created Date:  2008-11-03     Completed Date:  2008-12-16     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101193365     Medline TA:  J Neurol Phys Ther     Country:  United States    
Other Details:
Languages:  eng     Pagination:  110-7     Citation Subset:  IM    
Affiliation:
Program in Physical Therapy, University of Minnesota, Minneapolis, Minnesota, USA. tjk@umn.edu
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MeSH Terms
Descriptor/Qualifier:
Adult
Analysis of Variance
Brain Mapping / methods*
Case-Control Studies
Cognition / physiology*
Female
Humans
Image Processing, Computer-Assisted
Magnetic Resonance Imaging
Male
Memory / physiology
Middle Aged
Motor Cortex / physiology*
Motor Skills / physiology*
Stroke / physiopathology*
Visual Perception / physiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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