| Neural mechanisms underlying obesity and drug addiction. | |
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MedLine Citation:
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PMID: 17292426 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Increasing rates of obesity have alarmed health officials and prompted much public dialogue. While the factors leading to obesity are numerous, an inability to control intake of freely available food is central to the problem. In order to understand this, we need to better define the mechanisms by which the brain regulates food intake, and why it is often difficult to control consumption. From this point of view, it seems valuable to consider the commonalities between food intake and drug abuse. While research in the two fields has historically emphasized different neural substrates, recent data have increased interest in better defining elements that may underlie both drug addiction and obesity. Here we discuss some of these shared elements with an emphasis on emerging areas of research that better define common mechanisms leading to overconsumption. |
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Authors:
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Richard Trinko; Robert M Sears; Douglas J Guarnieri; Ralph J DiLeone |
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Publication Detail:
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Type: Journal Article; Review Date: 2007-01-16 |
Journal Detail:
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Title: Physiology & behavior Volume: 91 ISSN: 0031-9384 ISO Abbreviation: Physiol. Behav. Publication Date: 2007 Aug |
Date Detail:
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Created Date: 2007-08-20 Completed Date: 2007-11-28 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0151504 Medline TA: Physiol Behav Country: United States |
Other Details:
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Languages: eng Pagination: 499-505 Citation Subset: IM |
Affiliation:
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Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06519, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Behavior, Addictive / physiopathology*, psychology Brain / physiopathology Humans Obesity / physiopathology*, psychology Substance-Related Disorders / physiopathology*, psychology |
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