Document Detail


Neural mechanisms controlling jaw-jerk reflex in the cat.
MedLine Citation:
PMID:  16148746     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Signal substances of axon terminals presynaptic to jaw spindle Ia afferents and their ultrastructural features were examined using a combination of intra-axonal horseradish peroxidase injection and postembedding immunogold-labeling techniques in cats. A total of 35 axon terminals presynaptic to 22 horseradish peroxidase-labeled Ia boutons were examined. Of the 35 presynaptic axon terminals, 14 (40%) were immunoreactive for both gamma-aminobutyric acid and glycine, 9 (26%) for gamma-aminobutyric acid alone and 9 (26%) for glycine alone. The bouton volume, mitochondrial volume, active zone area, and apposed surface area were larger for Ia boutons than for presynaptic axon terminals, while each of the values is similar among the three types of presynaptic axon terminals. These results suggest that gamma-aminobutyric acid and glycine play an important role for modulating the jaw-jerk reflex presynaptically and that the smaller size of presynaptic axon terminals is important to prevent action potential generation from Ia afferents.
Authors:
Sang Kyoo Paik; Soo Jin Oh; Young Jin Son; Su Kyung Ma; Chang Hyeon Ahn; Sung Kyo Kim; Zheng Chang; Masayuki Moritani; Atsushi Yoshida; Yong Chul Bae
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Neuroreport     Volume:  16     ISSN:  0959-4965     ISO Abbreviation:  Neuroreport     Publication Date:  2005 Sep 
Date Detail:
Created Date:  2005-09-08     Completed Date:  2005-12-15     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9100935     Medline TA:  Neuroreport     Country:  England    
Other Details:
Languages:  eng     Pagination:  1565-8     Citation Subset:  IM    
Affiliation:
Department of Neurobiology, Graduate School of Dentistry, Kyungpook National University, Daegu, Korea.
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MeSH Terms
Descriptor/Qualifier:
Analysis of Variance
Animals
Axons / metabolism,  ultrastructure
Cats
Cell Count / methods
Glycine / metabolism
Horseradish Peroxidase / metabolism
Immunohistochemistry / methods
Jaw / physiology*
Microscopy, Immunoelectron / methods
Motor Neurons / metabolism,  physiology*,  ultrastructure
Muscle Spindles / metabolism
Nerve Fibers / metabolism
Presynaptic Terminals / metabolism,  ultrastructure
Reflex / physiology*
Trigeminal Nucleus, Spinal / cytology*
gamma-Aminobutyric Acid / metabolism
Chemical
Reg. No./Substance:
56-12-2/gamma-Aminobutyric Acid; 56-40-6/Glycine; EC 1.11.1.-/Horseradish Peroxidase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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