Document Detail

Neural correlates of response inhibition for behavioral regulation in humans assessed by functional magnetic resonance imaging.
MedLine Citation:
PMID:  11502357     Owner:  NLM     Status:  MEDLINE    
To identify the specific frontal and cingulate regions involved in response inhibition, five Chinese right-handed male volunteers with an attention span reaching or exceeding a 7-digit level participated in this blocked design functional magnetic resonance imaging study. Each block represented one of the two experimental conditions, the Correct Matching or the Incorrect Matching condition. In the Correct Matching condition, the subjects were required to make correct judgement of whether the two 3-digit numbers presented in succession were the same or not; whereas in the Incorrect Matching condition, the participants were instructed to inhibit the correct responses. Bilateral activations of the prefrontal and anterior cingulate as well as the left posterior cingulated cortex were observed while the subjects were exercising response inhibition. The roles of these activations in response inhibition were discussed.
T M Lee; H L Liu; C M Feng; J Hou; S Mahankali; P T Fox; J H Gao
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Neuroscience letters     Volume:  309     ISSN:  0304-3940     ISO Abbreviation:  Neurosci. Lett.     Publication Date:  2001 Aug 
Date Detail:
Created Date:  2001-08-14     Completed Date:  2001-10-11     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7600130     Medline TA:  Neurosci Lett     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  109-12     Citation Subset:  IM    
Neuropsychology Laboratory, Department of Psychology, The University of Hong Kong, Hong Kong.
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MeSH Terms
Attention / physiology
Behavior / physiology*
Brain Mapping
Cognition / physiology
Gyrus Cinguli / physiology*
Magnetic Resonance Imaging*
Neural Inhibition / physiology*
Prefrontal Cortex / physiology*

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