| Neural correlates of fear of movement in high and low fear-avoidant chronic low back pain patients: An event-related fMRI study. | |
| | |
MedLine Citation:
|
PMID: 22230805 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
The fear-avoidance model postulates that in chronic low back pain (CLBP) a fear of movement is acquired in the acute phase, which leads to subsequent avoidance of physical activity and contributes to the pain syndrome's becoming chronic. In the present event-related functional magnetic resonance imaging (fMRI) study of the neural correlates of the fear of movement, 60 women (30 CLBP patients, 15 healthy controls, and 15 women with spider phobia; mean age 46.8±9.8 years) participated. The CLBP patients were divided into a high and low fear-avoidant group on the basis of the Tampa Scale of Kinesiophobia. The participants viewed photographs depicting neutral and aversive (back-stressing) movements, generally fear-inducing and neutral pictures from the International Affective Picture System, and pictures of spiders while fMRI data were acquired. It was hypothesized that the high fear-avoidant CLBP patients would show fear-related activations when viewing the aversive movements and that they would differ from CLBP patients with low fear-avoidance and controls in this regard. No such activations were found for high or low fear-avoidant CLBP patients. The random-effects analysis showed no differences between high and low fear-avoidant CLBP patients or high fear-avoidant CLBP patients and controls. Normal fear-related activations were present in the high fear-avoidant CLBP patients for the generally fear-inducing pictures, demonstrating the validity of the stimulation paradigm and a generally unimpaired fear processing of the high fear-avoidant CLBP patients. Our findings do not support the fear component of the fear avoidance model. |
| | |
Authors:
|
Antonia Barke; Jürgen Baudewig; Carsten Schmidt-Samoa; Peter Dechent; Birgit Kröner-Herwig |
Related Documents
:
|
2869685 - Glomerulonephritis associated with takayasu's arteritis: report of three cases and revi... 21860965 - Comparison of clinical characteristics of patients with adductor laryngeal dystonia in ... 21250925 - Role of high-resolution computerized tomography (hrct) of the chest in granulomatous uv... 1466365 - Antineutrophil cytoplasmic antibodies: a still-growing class of autoantibodies in infla... 1424745 - Soluble interleukin-2 receptors in retinal vasculitis. 7074735 - The differential diagnosis of acute pericarditis from the normal variant: new electroca... |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2012-1-7 |
Journal Detail:
|
Title: Pain Volume: - ISSN: 1872-6623 ISO Abbreviation: - Publication Date: 2012 Jan |
Date Detail:
|
Created Date: 2012-1-10 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 7508686 Medline TA: Pain Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
|
Copyright © 2011 International Association for the Study of Pain. Published by Elsevier B.V. All rights reserved. |
Affiliation:
|
Georg-Elias-Müller-Institute of Psychology, Department of Clinical Psychology and Psychotherapy, University of Göttingen, Göttingen, Germany. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Opioids added to local anesthetics for single-shot intrathecal anesthesia in patients undergoing min...
Next Document: Proteomic characterization in the hippocampus of prenatally stressed rats.