| Neural tuning for face wholes and parts in human fusiform gyrus revealed by FMRI adaptation. | |
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MedLine Citation:
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PMID: 20505126 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Although the right fusiform face area (FFA) is often linked to holistic processing, new data suggest this region also encodes part-based face representations. We examined this question by assessing the metric of neural similarity for faces using a continuous carryover functional MRI (fMRI) design. Using faces varying along dimensions of eye and mouth identity, we tested whether these axes are coded independently by separate part-tuned neural populations or conjointly by a single population of holistically tuned neurons. Consistent with prior results, we found a subadditive adaptation response in the right FFA, as predicted for holistic processing. However, when holistic processing was disrupted by misaligning the halves of the face, the right FFA continued to show significant adaptation, but in an additive pattern indicative of part-based neural tuning. Thus this region seems to contain neural populations capable of representing both individual parts and their integration into a face gestalt. A third experiment, which varied the asymmetry of changes in the eye and mouth identity dimensions, also showed part-based tuning from the right FFA. In contrast to the right FFA, the left FFA consistently showed a part-based pattern of neural tuning across all experiments. Together, these data support the existence of both part-based and holistic neural tuning within the right FFA, further suggesting that such tuning is surprisingly flexible and dynamic. |
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Authors:
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Alison Harris; Geoffrey Karl Aguirre |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't Date: 2010-05-26 |
Journal Detail:
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Title: Journal of neurophysiology Volume: 104 ISSN: 1522-1598 ISO Abbreviation: J. Neurophysiol. Publication Date: 2010 Jul |
Date Detail:
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Created Date: 2010-07-08 Completed Date: 2011-01-07 Revised Date: 2011-08-01 |
Medline Journal Info:
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Nlm Unique ID: 0375404 Medline TA: J Neurophysiol Country: United States |
Other Details:
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Languages: eng Pagination: 336-45 Citation Subset: IM |
Affiliation:
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Department of Neurology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Eye Face / physiology* Female Functional Laterality / physiology Humans Image Processing, Computer-Assisted Magnetic Resonance Imaging Male Mouth Pattern Recognition, Visual / physiology Photic Stimulation Social Perception* Visual Cortex / physiology* Young Adult |
| Grant Support | |
ID/Acronym/Agency:
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K08 MH-72926-01/MH/NIMH NIH HHS |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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