| Neural responses to visual food stimuli after a normal vs. higher protein breakfast in breakfast-skipping teens: a pilot fMRI study. | |
| | |
MedLine Citation:
|
PMID: 21546927 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
This functional magnetic resonance imaging (fMRI) pilot study identified whether breakfast consumption would alter the neural activity in brain regions associated with food motivation and reward in overweight "breakfast skipping" (BS) adolescent girls and examined whether increased protein at breakfast would lead to additional alterations. Ten girls (Age: 15 ± 1 years; BMI percentile 93 ± 1%; BS 5 ± 1×/week) completed 3 testing days. Following the BS day, the participants were provided with, in randomized order, normal protein (NP; 18 ± 1 g protein) or higher protein (HP; 50 ± 1 g protein) breakfast meals to consume at home for 6 days. On day 7 of each pattern, the participants came to the laboratory to consume their respective breakfast followed by appetite questionnaires and an fMRI brain scan to identify brain activation responses to viewing food vs. nonfood images prior to lunch. Breakfast consumption led to enduring (i.e., 3-h post breakfast) reductions in neural activation in the hippocampus, amygdala, cingulate, and parahippocampus vs. BS. HP led to enduring reductions in insula and middle prefrontal cortex activation vs. NP. Hippocampal, amygdala, cingulate, and insular activations were correlated with appetite and inversely correlated with satiety. In summary, the addition of breakfast led to alterations in brain activation in regions previously associated with food motivation and reward with additional alterations following the higher-protein breakfast. These data suggest that increased dietary protein at breakfast might be a beneficial strategy to reduce reward-driven eating behavior in overweight teen girls. Due to the small sample size, caution is warranted when interpreting these preliminary findings. |
| | |
Authors:
|
Heather J Leidy; Rebecca J Lepping; Cary R Savage; Corey T Harris |
Related Documents
:
|
18969857 - Optimisation of focused-microwave assisted digestion procedure for kjeldahl nitrogen de... 21364287 - Food allergy. 10890517 - Thin-layer chromatography in food and agricultural analysis. 8712357 - Selection of reference or test materials for the validation of atomic absorption food a... 15469377 - Impact of food allergies on school nursing practice. 21281687 - The effect of pre-exposure and recovery type on activity-based anorexia in rats. |
Publication Detail:
|
Type: Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural Date: 2011-05-05 |
Journal Detail:
|
Title: Obesity (Silver Spring, Md.) Volume: 19 ISSN: 1930-739X ISO Abbreviation: Obesity (Silver Spring) Publication Date: 2011 Oct |
Date Detail:
|
Created Date: 2011-09-28 Completed Date: 2012-03-27 Revised Date: 2012-08-13 |
Medline Journal Info:
|
Nlm Unique ID: 101264860 Medline TA: Obesity (Silver Spring) Country: United States |
Other Details:
|
Languages: eng Pagination: 2019-25 Citation Subset: IM |
Affiliation:
|
Department of Dietetics & Nutrition, University of Kansas Medical Center, Kansas City, Kansas, USA. leidyh@missouri.edu |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adolescent Appetite / physiology* Body Mass Index Brain / physiology* Brain Mapping Diet Dietary Proteins / administration & dosage* Feeding Behavior / physiology* Female Food* Humans Magnetic Resonance Imaging Motivation / physiology Overweight / physiopathology, psychology* Photic Stimulation / methods Pilot Projects Questionnaires Reward Satiety Response / physiology* |
| Grant Support | |
ID/Acronym/Agency:
|
K12 HD052027-04/HD/NICHD NIH HHS |
| Chemical | |
Reg. No./Substance:
|
0/Dietary Proteins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Reducing obesity stigma: the effectiveness of cognitive dissonance and social consensus intervention...
Next Document: Body fat and racial genetic admixture are associated with aerobic fitness levels in a multiethnic pe...