| Networking health research in Britain: the post-war childhood leukaemia trials. | |
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MedLine Citation:
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PMID: 19569308 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The treatment of childhood leukaemia is seen as a successful historical example of the operation of the randomized controlled trial and continues to inform contemporary policy making on such trials within health research. This article analyses the scientists' 'story of success' through historical research. It tells us about the organizational and professional structures of such research post-war in the United Kingdom, and examines the history of the cancer clinical trial through this particular example. The story reveals a more complex picture than the 'heroic' one, with key developments in the operation of post-war science, both in terms of its infrastructure and of its scientific networks, not least the rise of co-operative working among clinicians and the growing importance of statisticians in medical research and practice. It also underlines differences between the British and US approaches in which the role of one health system, the National Health Service, helped structure different, initially less intensive, patterns of response. |
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Authors:
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Ornella Moscucci; Rachel Herring; Virginia Berridge |
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Publication Detail:
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Type: Historical Article; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: 20 century British history Volume: 20 ISSN: 0955-2359 ISO Abbreviation: 20 Century Br Hist Publication Date: 2009 |
Date Detail:
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Created Date: 2009-07-02 Completed Date: 2009-07-29 Revised Date: 2010-01-19 |
Medline Journal Info:
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Nlm Unique ID: 9015384 Medline TA: 20 Century Br Hist Country: England |
Other Details:
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Languages: eng Pagination: 23-52 Citation Subset: Q; QIS |
Affiliation:
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Centre for History in Public Health, London School of Hygiene and Tropical Medicine. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Biomedical Research
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history* Child Clinical Trials as Topic / history* Cooperative Behavior Great Britain History, 20th Century Humans Leukemia / history* Science / history State Medicine / history United States |
| Grant Support | |
ID/Acronym/Agency:
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//Medical Research Council |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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