| Nerve root enhancement on spinal MRI in pediatric Guillain-Barré syndrome. | |
| | |
MedLine Citation:
|
PMID: 20837305 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Guillain-Barré syndrome diagnosis is based on clinical presentation and supportive diagnostic testing. In its early stage, no single, reliable diagnostic test is available. However, a finding of nerve root enhancement on spinal magnetic resonance imaging may be useful. We evaluated the frequency of nerve root enhancement on spinal magnetic resonance imaging in children with Guillain-Barré syndrome. At a single tertiary pediatric center, we conducted a retrospective chart review of children with Guillain-Barré syndrome who had complete spinal or lumbosacral spinal magnetic resonance imaging with gadolinium administration from January 2002-January 2009. Twenty-four consecutive patients were identified. Spinal nerve root enhancement with gadolinium was present in 92% (22/24) of children with Guillain-Barré syndrome on initial spinal magnetic resonance imaging (95% confidence interval, 0.745-0.978). This finding increased to 100% of patients, after two patients underwent repeat spinal magnetic resonance imaging that did reveal nerve root enhancement. Patterns of enhancement were variable, but involved the thoracolumbar nerve roots in all patients. Enhancement of nerve roots with gadolinium on initial spinal magnetic resonance imaging was frequently present in these children with Guillain-Barré syndrome. Spinal magnetic resonance imaging is a sensitive diagnostic test and should be considered an additional diagnostic tool in select cases. |
| | |
Authors:
|
Sarah B Mulkey; Charles M Glasier; Bassem El-Nabbout; William D Walters; Christian Ionita; Michael H McCarthy; Gregory B Sharp; Rolla M Shbarou |
Related Documents
:
|
15660095 - 3d-ct evaluation of facial asymmetry. 11345015 - Magnetic resonance imaging of the peripheral nervous system. 1334065 - Nerve sheath tumors: evaluation with ct and mr imaging. 22381275 - Transplantation of human adipose-derived stem cells in a rabbit model of traumatic dege... 11559655 - Evidence for altered hepatic gluconeogenesis in patients with cirrhosis using in vivo 3... 21143525 - The association between paranasal computerized tomography scans and symptoms and signs ... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Pediatric neurology Volume: 43 ISSN: 1873-5150 ISO Abbreviation: Pediatr. Neurol. Publication Date: 2010 Oct |
Date Detail:
|
Created Date: 2010-09-14 Completed Date: 2011-01-21 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8508183 Medline TA: Pediatr Neurol Country: United States |
Other Details:
|
Languages: eng Pagination: 263-9 Citation Subset: IM |
Copyright Information:
|
Copyright © 2010 Elsevier Inc. All rights reserved. |
Affiliation:
|
Department of Pediatrics, University of Arkansas for Medical Sciences, Arkansas Children's Hospital, Little Rock, Arkansas 72202-3591, USA. mulkeysarah@uams.edu |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adolescent Child Child, Preschool Female Guillain-Barre Syndrome / pathology* Humans Lumbar Vertebrae Magnetic Resonance Imaging Male Retrospective Studies Spinal Nerve Roots / pathology* Young Adult |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Cerebral MRI and cognition in nonhandicapped, low birth weight adults.
Next Document: Severe hypernatremia in a hospitalized child: munchausen by proxy.