| Nerve growth factor synthesis by mouse submandibular gland cells in culture. | |
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MedLine Citation:
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PMID: 8242346 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Mouse submandibular gland (SMG) cells in culture rarely retain functional properties of SMG cells in vivo. We demonstrate that both primary SMG cells and the mouse SMG cell line SCA-9 secrete biologically active nerve growth factor (NGF). However, primary cells secrete 40-fold more NGF than SCA-9 cells, demonstrating that SCA-9 cells cannot substitute for primary SMG cells for the study of SMG NGF in vitro. |
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Authors:
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M Fahnestock; Q Lu |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Brain research Volume: 621 ISSN: 0006-8993 ISO Abbreviation: Brain Res. Publication Date: 1993 Sep |
Date Detail:
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Created Date: 1993-12-23 Completed Date: 1993-12-23 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0045503 Medline TA: Brain Res Country: NETHERLANDS |
Other Details:
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Languages: eng Pagination: 339-42 Citation Subset: IM |
Affiliation:
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Department of Biomedical Sciences, McMaster University, Hamilton, Ont., Canada. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Cells, Cultured Male Mice Nerve Growth Factors / biosynthesis* Submandibular Gland / cytology, metabolism* |
| Grant Support | |
ID/Acronym/Agency:
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DE10448/DE/NIDCR NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Nerve Growth Factors |
| Comments/Corrections | |
Erratum In:
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Brain Res 1993 Nov 19;628(1-2):356 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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