Document Detail


Nerve growth factor synthesis by mouse submandibular gland cells in culture.
MedLine Citation:
PMID:  8242346     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Mouse submandibular gland (SMG) cells in culture rarely retain functional properties of SMG cells in vivo. We demonstrate that both primary SMG cells and the mouse SMG cell line SCA-9 secrete biologically active nerve growth factor (NGF). However, primary cells secrete 40-fold more NGF than SCA-9 cells, demonstrating that SCA-9 cells cannot substitute for primary SMG cells for the study of SMG NGF in vitro.
Authors:
M Fahnestock; Q Lu
Related Documents :
4022136 - Very rapid turnover of dopamine in noradrenaline cell body regions.
8313996 - Responses to camp depend on stage of neuronal differentiation of ngf-treated adrenal ch...
1422316 - Cytological and ultrastructural investigation on osteoblastic and preosteoclastic cells...
3005866 - Inhibition of growth factor-induced differentiation of pc12 cells by microinjection of ...
817636 - Immunofluorescent studies in experimental middle ear effusions.
24356076 - Micrornas contribute to promyelocyte apoptosis in as2o3-treated apl cells.
Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Brain research     Volume:  621     ISSN:  0006-8993     ISO Abbreviation:  Brain Res.     Publication Date:  1993 Sep 
Date Detail:
Created Date:  1993-12-23     Completed Date:  1993-12-23     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0045503     Medline TA:  Brain Res     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  339-42     Citation Subset:  IM    
Affiliation:
Department of Biomedical Sciences, McMaster University, Hamilton, Ont., Canada.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Cells, Cultured
Male
Mice
Nerve Growth Factors / biosynthesis*
Submandibular Gland / cytology,  metabolism*
Grant Support
ID/Acronym/Agency:
DE10448/DE/NIDCR NIH HHS
Chemical
Reg. No./Substance:
0/Nerve Growth Factors
Comments/Corrections
Erratum In:
Brain Res 1993 Nov 19;628(1-2):356

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Disturbances in the performance of thermal discrimination tasks following cortical ablations in rats...
Next Document:  Neuropeptide Y in the arcuate nucleus is modulated by alterations in glucose utilization.