Document Detail


Nephrotoxicity by dicloxacillin and gentamicin in 163 patients with intertrochanteric hip fractures.
MedLine Citation:
PMID:  10990387     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Of 163 patients with intertrochanteric hip fractures 87 received 2 g dicloxacillin and 240 mg of gentamicin preoperatively, and 76 patients had no antibiotic prophylaxis. Preoperative antibiotic prophylaxis was not shown to have any significant effect on wound infections. However, 16 reversible and 1 irreversible cases of kidney toxicity were found among patients receiving antibiotic prophylaxis, whereas there were only four cases of reversible kidney damage among the patients not receiving antibiotics.
Authors:
L Solgaard; J I Tuxoe; M Mafi; S Due Olsen; T Toftgaard Jensen
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International orthopaedics     Volume:  24     ISSN:  0341-2695     ISO Abbreviation:  Int Orthop     Publication Date:  2000  
Date Detail:
Created Date:  2000-12-15     Completed Date:  2001-01-04     Revised Date:  2013-04-12    
Medline Journal Info:
Nlm Unique ID:  7705431     Medline TA:  Int Orthop     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  155-7     Citation Subset:  IM    
Affiliation:
Department of Orthopaedics, H:S Hvidovre Hospital, Hvidovre, Denmark. solgaard_lars@hotmail.com
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aged, 80 and over
Anti-Bacterial Agents / adverse effects*
Antibiotic Prophylaxis*
Creatinine / blood
Dicloxacillin / adverse effects*
Female
Gentamicins / adverse effects*
Hip Fractures / surgery*
Humans
Kidney Diseases / blood,  chemically induced*
Male
Middle Aged
Penicillins / adverse effects*
Preoperative Care
Regression Analysis
Retrospective Studies
Statistics, Nonparametric
Chemical
Reg. No./Substance:
0/Anti-Bacterial Agents; 0/Gentamicins; 0/Penicillins; 3116-76-5/Dicloxacillin; 60-27-5/Creatinine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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