Document Detail


Nephrotic syndrome with mesangial proliferative glomerulonephritis induced by multiple wasp stings.
MedLine Citation:
PMID:  10085454     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We report the case of a young male who developed severe nephrotic syndrome within 2-3 weeks after being stung by 3 wasps. A percutaneous kidney biopsy specimen revealed mesangioproliferative glomerulonephritis with occasional subepithelial deposits suggestive of early membranous nephropathy. The patient was treated with oral prednisone 60 mg/day with no significant clinical response after 4 weeks, at which point he was started on oral cyclophosphamide, 100 mg/day, while the prednisone dose was tapered to 20 mg every other day over a 2-week period. Six months after initiation of cyclophosphamide, he still has severe nephrotic syndrome. We also briefly review the literature on Hymenoptera sting associated nephrotic syndrome.
Authors:
B Tauk; H Hachem; B Bastani
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  American journal of nephrology     Volume:  19     ISSN:  0250-8095     ISO Abbreviation:  Am. J. Nephrol.     Publication Date:  1999  
Date Detail:
Created Date:  1999-07-08     Completed Date:  1999-07-08     Revised Date:  2007-02-14    
Medline Journal Info:
Nlm Unique ID:  8109361     Medline TA:  Am J Nephrol     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  70-2     Citation Subset:  IM    
Affiliation:
DePaul Medical Center, Saint Louis University Health Sciences Center, St. Louis, Mo., USA.
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MeSH Terms
Descriptor/Qualifier:
Adult
Animals
Anti-Inflammatory Agents / therapeutic use
Cyclophosphamide / therapeutic use
Glomerulonephritis, Membranoproliferative / drug therapy,  etiology*
Humans
Immunosuppressive Agents / therapeutic use
Insect Bites and Stings / complications*
Male
Nephrotic Syndrome / drug therapy,  etiology*
Prednisone / therapeutic use
Wasps*
Chemical
Reg. No./Substance:
0/Anti-Inflammatory Agents; 0/Immunosuppressive Agents; 50-18-0/Cyclophosphamide; 53-03-2/Prednisone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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