| Nephrotic syndrome with massive accumulation of type I and type III collagen in the glomeruli. | |
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MedLine Citation:
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PMID: 8507929 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A 54-year-old woman with nephrotic syndrome underwent renal biopsy. By light microscopy, the glomerular capillary lumen was remarkably narrowed because of diffuse accumulation of Periodic acid Shiff (PAS) positive material along the glomerular capillary wall. By electron microscopy, collagenous fibers were observed in the mesangium and subendothelial area. The fibrous material reacted with antibodies against type I and III collagen but not with those against laminin or type IV collagen by an indirect immunofluorescence technique. This case seemed to be a case of collagenofibrotic glomerulonephropathy. |
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Authors:
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F Yoshida; Y Yuzawa; H Shigematsu; A Ito; C Yamazaki; K Yoshioka; A Ooshima; S Matsuo |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Internal medicine (Tokyo, Japan) Volume: 32 ISSN: 0918-2918 ISO Abbreviation: Intern. Med. Publication Date: 1993 Feb |
Date Detail:
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Created Date: 1993-07-15 Completed Date: 1993-07-15 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 9204241 Medline TA: Intern Med Country: JAPAN |
Other Details:
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Languages: eng Pagination: 171-6 Citation Subset: IM |
Affiliation:
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Third Department of Internal Medicine, Nagoya University School of Medicine, Japan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Collagen
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biosynthesis* Female Fluorescent Antibody Technique Humans Immunohistochemistry Kidney Glomerulus / metabolism*, ultrastructure Middle Aged Nephrotic Syndrome / metabolism*, pathology |
| Chemical | |
Reg. No./Substance:
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9007-34-5/Collagen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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