Document Detail


Nephrotic syndrome in chronic lymphocytic leukaemia.
MedLine Citation:
PMID:  4279123     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Two patients with chronic lymphocytic leukaemia and the nephrotic syndrome are described in whom deposits were shown in renal glomerular basement membranes in a pattern suggesting immune-complex glomerulonephritis. This renal lesion has been described in one case of squamous carcinoma of the bronchus, in one case of Burkitt's lymphoma, and in three cases of Hodgkin's disease though not previously in chronic lymphocytic leukaemia. Immune-complex glomerulonephritis is, however, a recognized finding in mice infected with leukaemogenic viruses
Authors:
J R Dathan; M F Heyworth; A G MacIver
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  British medical journal     Volume:  3     ISSN:  0007-1447     ISO Abbreviation:  Br Med J     Publication Date:  1974 Sep 
Date Detail:
Created Date:  1975-01-22     Completed Date:  1975-01-22     Revised Date:  2010-10-26    
Medline Journal Info:
Nlm Unique ID:  0372673     Medline TA:  Br Med J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  655-7     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Aged
Basement Membrane / pathology,  ultrastructure
Biopsy
Blood Proteins / analysis
Bone Marrow / pathology
Chlorambucil / therapeutic use
Complement System Proteins / analysis
Edema / complications
Fluorescent Antibody Technique
Furosemide / therapeutic use
Humans
Hypertension / complications
Immune Complex Diseases / pathology
Immunoglobulin A / analysis
Immunoglobulin G / analysis
Immunoglobulin M / analysis
Kidney Glomerulus / pathology,  ultrastructure
Leukemia, Lymphoid / complications*
Leukocyte Count
Male
Microscopy, Electron
Middle Aged
Nephrotic Syndrome / complications*,  drug therapy,  therapy
Proteinuria
Spironolactone / therapeutic use
Chemical
Reg. No./Substance:
0/Blood Proteins; 0/Immunoglobulin A; 0/Immunoglobulin G; 0/Immunoglobulin M; 305-03-3/Chlorambucil; 52-01-7/Spironolactone; 54-31-9/Furosemide; 9007-36-7/Complement System Proteins
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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