Document Detail


Nephrotic syndrome in chronic lymphocytic leukemia: a paraneoplastic syndrome?
MedLine Citation:
PMID:  11140811     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The association of malignancy and various glomerulopathies is a well recognized phenomenon. We report a case of nephrotic syndrome secondary to minimal-change disease in a patient with chronic lymphocytic leukemia (CLL) and review the literature on nephrotic syndrome in this disorder. Since the relative distribution of etiologies differ from what might be expected for primary nephrotic syndrome in a similar aged population, we propose that nephrotic syndrome is a potential paraneoplastic phenomenon associated with CLL. We hypothesize a possible etiologic role of different cell surface markers of the lymphocyte to explain the diverse renal histologic manifestations.
Authors:
N Aslam; N I Nseir; J F Viverett; S I Bastacky; J P Johnson
Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Clinical nephrology     Volume:  54     ISSN:  0301-0430     ISO Abbreviation:  Clin. Nephrol.     Publication Date:  2000 Dec 
Date Detail:
Created Date:  2001-01-03     Completed Date:  2001-05-10     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0364441     Medline TA:  Clin Nephrol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  492-7     Citation Subset:  IM    
Affiliation:
Renal and Electrolyte Division, University of Pittsburgh School of Medicine, PA 15261, USA.
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MeSH Terms
Descriptor/Qualifier:
Aged
Humans
Kidney Glomerulus / pathology*
Leukemia, Lymphocytic, Chronic, B-Cell / complications*,  diagnosis
Male
Nephrotic Syndrome / diagnosis,  etiology*
Paraneoplastic Syndromes / diagnosis,  etiology
Tomography, X-Ray Computed

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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