Document Detail


Nephrotic syndrome from the genetic point of view.
MedLine Citation:
PMID:  20191883     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Nephrotic syndrome, an entity described at the beginning of the 20th century, has still an unclear pathophysiology, genetic and immunologic factors being incriminated. Here we report three cases of nephrotic syndrome with genetic involvement. The article presented tremendous progress that have been made over the past few years in enhancing our understanding of the slit-diaphragm and podocyte biology and genetics involvement in nephrotic syndrome.
Authors:
Florentina Cucer; Cristina Rusu; R Muller; Mihaela Munteanu; Doina Mihăilă; Ingrith Miron; O Brumariu
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Revista medico-chirurgicală̆ a Societă̆ţ̜ii de Medici ş̧i Naturaliş̧ti din Iaş̧i     Volume:  113     ISSN:  0048-7848     ISO Abbreviation:  Rev Med Chir Soc Med Nat Iasi     Publication Date:    2009 Oct-Dec
Date Detail:
Created Date:  2010-03-02     Completed Date:  2010-05-14     Revised Date:  2011-01-13    
Medline Journal Info:
Nlm Unique ID:  0413735     Medline TA:  Rev Med Chir Soc Med Nat Iasi     Country:  Romania    
Other Details:
Languages:  eng     Pagination:  1107-12     Citation Subset:  IM    
Affiliation:
IVth Pediatric Clinic, School of Medicine,"Gr.T. Popa" University of Medicine and Pharmacy, Iaşi.
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MeSH Terms
Descriptor/Qualifier:
Child, Preschool
Consanguinity
Fatal Outcome
Female
Humans
Infant
Introns
Male
Membrane Proteins / genetics*
Nephrotic Syndrome / drug therapy,  genetics*,  physiopathology
Sequence Deletion / genetics
Chemical
Reg. No./Substance:
0/Membrane Proteins; 0/nephrin

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