| Nephrotic syndrome and focal glomerular sclerosis in aging man. | |
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MedLine Citation:
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PMID: 662049 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Focal glomerular sclerosis (FGS) with the nephrotic syndrome is a disecades. Less than 2% of reported patients are older than 60 years of age, and to our knowledge no patients over 70 years of age have been described. The present report documents with renal biopsies the occurrence of FGS and the nephrotic syndrome in 4 patients with an average age of 70 years, 3 being septuagenarians. We suggest that FGS in these patients may represent a disease of senescence, and that FGS in younger patients may result from accelerated glomerulotubular senescence. |
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Authors:
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W K Bolton; F B Westervelt; B C Sturgill |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Nephron Volume: 20 ISSN: 0028-2766 ISO Abbreviation: Nephron Publication Date: 1978 |
Date Detail:
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Created Date: 1978-08-28 Completed Date: 1978-08-28 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0331777 Medline TA: Nephron Country: SWITZERLAND |
Other Details:
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Languages: eng Pagination: 307-15 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Age Factors Aged Animals Child Edema / complications Female Heart Diseases / complications Humans Immunoglobulin M / analysis Kidney Glomerulus / pathology*, ultrastructure Male Middle Aged Nephrosclerosis / complications, immunology, pathology* Nephrotic Syndrome / complications, pathology* Rats |
| Chemical | |
Reg. No./Substance:
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0/Immunoglobulin M |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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