Document Detail


Nephrotic syndrome due to focal glomerulosclerosis and undifferentiated carcinoma.
MedLine Citation:
PMID:  11105803     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In neoplastic disorder-related nephrotic syndrome, focal glomerulosclerosis (FGS) has been reported mainly in hematological disorders like minimal change nephrotic syndrome (MCNS) in association with presumed T lymphocyte dysfunction. The association of FGS with cancer or solid tumor is rare. We report a case of nephrotic syndrome due to FGS in a patient with undifferentiated adenocarcinoma of the cystic duct. Although the underlying mechanism is unclear, the development of FGS seemed to be related to the poor histological differentiation of the cancer in the possibility of production of an active peptide.
Authors:
T Konoshita; M Itoh; S Hatakeyama; M Hirata; I Koni; R Miyazaki; Y Tofuku; H Mabuchi
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Clinical nephrology     Volume:  54     ISSN:  0301-0430     ISO Abbreviation:  Clin. Nephrol.     Publication Date:  2000 Nov 
Date Detail:
Created Date:  2001-03-29     Completed Date:  2001-05-31     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0364441     Medline TA:  Clin Nephrol     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  404-8     Citation Subset:  IM    
Affiliation:
Health Care Centre, Japan Advanced Institute of Science and Technology, Asahidai, Tatsunokuchi.
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MeSH Terms
Descriptor/Qualifier:
Adenocarcinoma / complications*,  pathology
Aged
Aged, 80 and over
Bile Duct Neoplasms / complications*,  pathology
Cystic Duct*
Female
Glomerulosclerosis, Focal Segmental / complications*,  pathology
Humans
Nephrotic Syndrome / etiology*,  pathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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