| Nephrotic syndrome associated with lithium therapy. | |
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MedLine Citation:
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PMID: 7249424 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Two patients on long-term lithium therapy developed the nephrotic syndrome. Ultrastructural study of a renal biopsy in each case showed extensive glomerular epithelial cell foot process fusion. Lithium was withdrawn in each case. The nephrotic syndrome cleared without steroid therapy and has not recurred 18 months later in one patient. The other patient required a further course of treatment with lithium and the nephrotic syndrome returned. Further biopsy revealed a more severe glomerular lesion. The nephrotic syndrome responded again to withdrawal of lithium and institution of steroid therapy. Lithium is known to cause acute renal failure and tubulo-interstitial disease, but the recently described association with proteinuria or nephrotic syndrome is little recognized. |
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Authors:
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F Alexander; J Martin |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Clinical nephrology Volume: 15 ISSN: 0301-0430 ISO Abbreviation: Clin. Nephrol. Publication Date: 1981 May |
Date Detail:
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Created Date: 1981-09-25 Completed Date: 1981-09-25 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0364441 Medline TA: Clin Nephrol Country: GERMANY, WEST |
Other Details:
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Languages: eng Pagination: 267-71 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Biopsy Bipolar Disorder / drug therapy Female Humans Lithium / adverse effects*, therapeutic use Male Middle Aged Nephrotic Syndrome / chemically induced*, pathology |
| Chemical | |
Reg. No./Substance:
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7439-93-2/Lithium |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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