Document Detail


Nephrotic syndrome as paraneoplastic manifestation of a primary pulmonary lymphoepithelioma-like carcinoma.
MedLine Citation:
PMID:  19761726     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We present a case of nephrotic syndrome secondary to a membranous glomerulonephritis (MG), in a nonsmoking female with a solitary pulmonary nodule, which did not show growth during 2 years of followup. A biopsy by videothoracoscopy showed a granulomatous non-neoplastic process with giant multinucleated cells. The appearance of a nephrotic syndrome and its interpretation as paraneoplastic revealed the existence of a primary pulmonary lymphoepithelioma-like carcinoma (LELC), a very rare pulmonary tumor. After resection of tumor there was a complete recovery from the nephrotic syndrome. This case highlights how the investigation of paraneoplastic syndromes can help in the early diagnosis of some malignancies.
Authors:
M D Arenas; M T Gil; T Malek; J Farré; F J Fernández Morejón; J M Arriero; I Aranda; A Moledous; F Alvarez-Ude
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Clinical nephrology     Volume:  72     ISSN:  0301-0430     ISO Abbreviation:  Clin. Nephrol.     Publication Date:  2009 Sep 
Date Detail:
Created Date:  2009-09-18     Completed Date:  2009-12-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0364441     Medline TA:  Clin Nephrol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  206-10     Citation Subset:  IM    
Affiliation:
Servicio de Nefrologia, Hospital Perpetuo Socorro, Alicante, Spain. arenasd@perpertuosocorro.nehos.com
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MeSH Terms
Descriptor/Qualifier:
Carcinoma / complications*
Female
Humans
Lung Neoplasms / complications*
Middle Aged
Nephrotic Syndrome / etiology*
Paraneoplastic Syndromes / etiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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