| Nephrotic syndrome and Hodgkin disease in children: a report of five cases. | |
| | |
MedLine Citation:
|
PMID: 9083769 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
This report documents the occurrence of a nephrotic syndrome in five children with Hodgkin disease. In two cases the nephrotic syndrome predated the diagnosis of lymphoma by 6 months and 12 months respectively, while in the other three, the two disorders occurred simultaneously. The nephrotic syndrome resolved in four cases during effective treatment for active Hodgkin disease, while proteinuria remained unchanged in the fifth case with partial control of the lymphoma. The occurrence of a nephrotic syndrome as a manifestation of active Hodgkin disease suggests that some immunological abnormalities play a role in the pathogenesis of the association. CONCLUSION: The possibility of glomerular dysfunction although rare must be considered and actively looked for in all cases of Hodgkin disease. Similarly, any unusual sign or symptom noted in patients with nephrotic syndrome, particularly receiving or having received immunosuppressants, requires thorough investigation to determine the presence or absence of lymphoma. |
| | |
Authors:
|
J L Stéphan; G Deschênes; Y Pérel; B Bader-Meunier; M Brunat-Mentigny; O Lejars; J P Lamagnères |
Related Documents
:
|
15265159 - The pediatric nephrotic syndrome spectrum: clinical homogeneity and molecular heterogen... 2465229 - Plasminogen activator in nephrotic syndrome. 16183409 - An adult with acute poststreptococcal glomerulonephritis complicated by hemolytic uremi... 421189 - Retroperitoneal paraganglioma and systemic amyloidosis: a case report. 8938689 - Successful erythropoietin treatment for severe anemia in nephrotic syndrome without ren... 20647659 - Successful treatment of dwarfism secondary to long-term steroid therapy in steroid-depe... 12026239 - Epileptic disorder as the first neurologic manifestation of blue rubber bleb nevus synd... 18325199 - Turner syndrome - an accidental finding? 19834709 - A rare trigger for macrophage activation syndrome. |
Publication Detail:
|
Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: European journal of pediatrics Volume: 156 ISSN: 0340-6199 ISO Abbreviation: Eur. J. Pediatr. Publication Date: 1997 Mar |
Date Detail:
|
Created Date: 1997-06-25 Completed Date: 1997-06-25 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 7603873 Medline TA: Eur J Pediatr Country: GERMANY |
Other Details:
|
Languages: eng Pagination: 239-42 Citation Subset: IM |
Affiliation:
|
Unité d' Oncologie Pédiatrique, St Etienne, France. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adolescent Biopsy, Needle Child Combined Modality Therapy Complement C1q / analysis Complement C3 / analysis Female Glomerular Mesangium / immunology, pathology Hodgkin Disease / diagnosis*, immunology, therapy Humans Immunoglobulin M / analysis Male Nephrotic Syndrome / diagnosis*, immunology, therapy Proteinuria / diagnosis, immunology, therapy Remission Induction |
| Chemical | |
Reg. No./Substance:
|
0/Complement C3; 0/Immunoglobulin M; 80295-33-6/Complement C1q |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: [18F]-fluorodeoxyglucose-positron emission tomography findings in protein infants with severe perive...
Next Document: Dopamine D2 receptors play a role in the (-)-apomorphine-like discriminative stimulus effects of (+)...