Document Detail


Nephrotic syndrome and Guillan-Barr? Syndrome: a rare association in child.
MedLine Citation:
PMID:  20061709     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Only few cases of nephrotic syndrome associated with Guillain-Barre Syndrome (GBS) have been reported in the adult and pediatric literature. A 3-year-old boy was initially admitted to our hospital following five days of progressive weakness of his extremities, fatigue, right leg pain and numbness. There was no past history of renal or neurological disease. Cerebro-spinal fluid studies showed a protein level of 92 mg/dL and a white cell count of 1 per high-power field. The diagnosis of GBS was verified with a nerve conduction velocity test as well as. The GBS symptoms improved gradually on intravenous immunoglobulin. Three weeks later, he developed severe proteinuria and edema; laboratory investigation showed nephrotic syndrome which responded to steroid therapy. Renal biopsy showed minimal change glomerulonephritis. He remained free of proteinuria during his 20 months of follow-up.
Authors:
Olfa Bouyahia; Ibtissem Khelifi; Lamia Gharsallah; Kais Harzallah; Sonia Mazigh Mrad; Tahar Ghargah; Samir Boukthir; Sammoud El Gharbi Azza
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia     Volume:  21     ISSN:  1319-2442     ISO Abbreviation:  Saudi J Kidney Dis Transpl     Publication Date:  2010 Jan 
Date Detail:
Created Date:  2010-01-11     Completed Date:  2010-03-11     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9436968     Medline TA:  Saudi J Kidney Dis Transpl     Country:  Saudi Arabia    
Other Details:
Languages:  eng     Pagination:  135-7     Citation Subset:  IM    
Affiliation:
Pediatric's Department, Children's Hospital of Tunis, Tunisia. olfa.bouyahia@rns.tn
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Biopsy
Child, Preschool
Fatigue / etiology
Female
Guillain-Barre Syndrome / complications*,  diagnosis,  drug therapy
Humans
Hypesthesia / etiology
Immunoglobulins, Intravenous / therapeutic use
Leg
Male
Middle Aged
Muscle Weakness / etiology
Nephrotic Syndrome / diagnosis,  drug therapy,  etiology*
Neurologic Examination
Pain / etiology
Steroids / therapeutic use
Treatment Outcome
Chemical
Reg. No./Substance:
0/Immunoglobulins, Intravenous; 0/Steroids

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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