| Nephrotic syndrome complicated by life-threatening pulmonary embolism in an adult patient. | |
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MedLine Citation:
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PMID: 20123597 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We report a 23-year-old male presenting with edema. He was originally admitted for an elective renal biopsy for diagnosis of renal pathology. Unfortunately, because of acute abdominal pain an exploratory laparotomy was done. Progressive azotemia and oliguria then developed, and he required temporary hemodialysis. However, he suffered from sudden-onset severe respiratory distress, and blood gas analysis showed profound hypoxemia with a marked arterial-alveolar oxygen difference. Assessment of a pulmonary embolism by radioisotope imaging was not possible because of his dependence on mechanical ventilation. Subcutaneous low molecular weight heparin and intravenous methylprednisolone were given to treat the presumed pulmonary embolism and the underlying nephrotic syndrome. His partial oxygen level gradually increased after continuous heparin and steroid administration. Complete obliteration of one major pulmonary artery and partial obliteration of other smaller arteries were revealed by magnetic resonance angiography. He was discharged and followed-up as an outpatient, and was given oral warfarin and prednisolone. Follow-up magnetic resonance angiography 5 months later showed a normal pulmonary tree with no residual lesions. |
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Authors:
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Szu-Chia Chen; Wan-Chun Liu; Cheng-Hsueh Lee; Jer-Ming Chang; Hung-Chun Chen |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: The Kaohsiung journal of medical sciences Volume: 26 ISSN: 1607-551X ISO Abbreviation: Kaohsiung J. Med. Sci. Publication Date: 2010 Feb |
Date Detail:
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Created Date: 2010-02-03 Completed Date: 2010-05-25 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100960562 Medline TA: Kaohsiung J Med Sci Country: China (Republic : 1949- ) |
Other Details:
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Languages: eng Pagination: 89-95 Citation Subset: IM |
Affiliation:
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Department of Internal Medicine, Kaohsiung Municipal Hsiao-Kang Hospital, Kaohsiung, Taiwan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Heparin, Low-Molecular-Weight
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therapeutic use Humans Magnetic Resonance Angiography Male Nephrotic Syndrome / complications*, drug therapy Pulmonary Artery / radiography Pulmonary Embolism / drug therapy, etiology*, radiography Young Adult |
| Chemical | |
Reg. No./Substance:
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0/Heparin, Low-Molecular-Weight |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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