Document Detail


Nephrolithiasis as primary symptom in sarcoidosis.
MedLine Citation:
PMID:  16019774     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A 30-year-old black woman presented with a 1-year history of repeated episodes of worsening weight loss and fatigue. Physical examination showed no skin lesions and a chest roentgenogram was normal. Workup showed no obvious cause of recurrent renal stones. Finally, the detection of lymphadenopathy led to the diagnosis of extrapulmonary sarcoidosis. Up to 4% of all cases of sarcoidosis may present with urolithiasis only. Renal stones may be more common in severe cases of sarcoidosis, which affect blacks most frequently. Although not generally recommended for diagnostic purposes in sarcoidosis, in this case determination of the angiotensin-converting enzyme level was helpful in making the correct diagnosis. It is important that physicians are aware of the possibility that sarcoidosis may present as urolithiasis, even in the presence of a negative chest roentgenogram.
Authors:
Kamran Darabi; Gilberto Torres; Daranee Chewaproug
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Scandinavian journal of urology and nephrology     Volume:  39     ISSN:  0036-5599     ISO Abbreviation:  Scand. J. Urol. Nephrol.     Publication Date:  2005  
Date Detail:
Created Date:  2005-07-15     Completed Date:  2005-09-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0114501     Medline TA:  Scand J Urol Nephrol     Country:  Sweden    
Other Details:
Languages:  eng     Pagination:  173-5     Citation Subset:  IM    
Affiliation:
Department of Medicine, Albert Einstein Medical Center, Philadelphia, Pennsylvania, USA. kamrandarabi@yahoo.com
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MeSH Terms
Descriptor/Qualifier:
Adult
Biological Markers / blood
Biopsy
Cholagogues and Choleretics / therapeutic use
Diagnosis, Differential
Female
Follow-Up Studies
Humans
Kidney Calculi / diagnosis,  etiology*,  therapy
Lithotripsy
Lymph Nodes / pathology
Peptidyl-Dipeptidase A / blood
Recurrence
Sarcoidosis / complications*,  diagnosis,  enzymology
Tomography, X-Ray Computed
Ursodeoxycholic Acid / therapeutic use
Chemical
Reg. No./Substance:
0/Biological Markers; 0/Cholagogues and Choleretics; 128-13-2/Ursodeoxycholic Acid; EC 3.4.15.1/Peptidyl-Dipeptidase A

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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