| Nephrogenic systemic fibrosis with multiple calcification and osseous metaplasia. | |
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MedLine Citation:
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PMID: 19002346 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We describe here a 50-year-old Japanese man with nephrogenic systemic fibrosis. He had been suffering from chronic renal insufficiency and had been treated with haemodialysis. He had undergone magnetic resonance angiography using gadodiamide 7 years previously. One month after magnetic resonance angiography, he noted swelling, hotness, induration and pain in his left arm. The same symptoms gradually spread over his lower extremities, resulting in flexion contractures with limited range of motion. Physical examination revealed skin sclerosis on his extremities with a glossy brownish skin surface. Histologically, increased collagen fibres with high cellularity were seen in the dermis and subcutaneous septa. Thickened fascia was also noted, as well as osseous metaplasia under the fascia. Computed tomography of the whole body revealed multiple calcification of the fascia in many muscles. Treatment with intravenous sodium thiosulphate did not result in any clinical improvement. |
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Authors:
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Yayoi Nagai; Michiko Hasegawa; Kahori Shinmi; Chikako Kishi; Yoshito Tsushima; Keigo Endo; Kazuhiko Okabe; Kazuhiro Suzuki; Osamu Ishikawa |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Acta dermato-venereologica Volume: 88 ISSN: 0001-5555 ISO Abbreviation: Acta Derm. Venereol. Publication Date: 2008 |
Date Detail:
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Created Date: 2008-11-12 Completed Date: 2009-01-27 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0370310 Medline TA: Acta Derm Venereol Country: Sweden |
Other Details:
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Languages: eng Pagination: 597-600 Citation Subset: IM |
Affiliation:
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Department of Dermatology, Gunma University Graduate School of Medicine, Gunma, Japan. yanagai@showa.gunma-u.ac.jp |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Calcinosis / radiography* Contrast Media / adverse effects* Fascia / radiography Gadolinium DTPA / adverse effects* Humans Kidney Failure, Chronic / surgery Kidney Transplantation Magnetic Resonance Angiography Male Muscular Diseases / radiography* Nephrogenic Fibrosing Dermopathy / chemically induced*, diagnosis Ossification, Heterotopic / radiography* Renal Dialysis Tomography, X-Ray Computed |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media; 122795-43-1/gadodiamide; 80529-93-7/Gadolinium DTPA |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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