Document Detail

Nephrogenic systemic fibrosis: an emerging threat among renal patients.
MedLine Citation:
PMID:  16689966     Owner:  NLM     Status:  MEDLINE    
Nephrogenic systemic fibrosis (NSF), also known as nephrogenic fibrosing dermopathy, is a scleroderma-like disease of the skin observed in patients with renal insufficiency. Since its recognition in 1997, relatively little has been published in the nephrology literature, despite indications that the disorder is becoming increasingly recognized in the United States and abroad. As nephrology professionals may be the first to encounter newly developing cases of NSF, it becomes imperative that they be able to recognize the symptoms and comorbidities and initiate tests and treatment. To date, the cause of NSF has not been established. Recent observations indicate that specific cells normally involved in wound repair and tissue remodeling may be aberrantly recruited to the skin and soft tissues of NSF patients.
Danielle M DeHoratius; Shawn E Cowper
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Publication Detail:
Type:  Editorial; Research Support, N.I.H., Extramural; Review    
Journal Detail:
Title:  Seminars in dialysis     Volume:  19     ISSN:  0894-0959     ISO Abbreviation:  Semin Dial     Publication Date:    2006 May-Jun
Date Detail:
Created Date:  2006-05-12     Completed Date:  2007-02-06     Revised Date:  2007-12-03    
Medline Journal Info:
Nlm Unique ID:  8911629     Medline TA:  Semin Dial     Country:  United States    
Other Details:
Languages:  eng     Pagination:  191-4     Citation Subset:  IM    
Department of Dermatology, Yale University School of Medicine, New Haven, Connecticut, USA.
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MeSH Terms
Diagnosis, Differential
Fibrosis / etiology
Kidney Failure, Chronic / complications*,  pathology
Skin Diseases / etiology*,  pathology
Thrombophilia / etiology
Thrombosis / etiology
Grant Support

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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