Document Detail

Nephrogenic fibrosing dermopathy in two patients with systemic lupus erythematosus.
MedLine Citation:
PMID:  15462493     Owner:  NLM     Status:  MEDLINE    
Nephrogenic fibrosing dermopathy (NFD) is a novel fibrosing disorder of the skin with characteristic histopathology. It affects patients with impaired renal function and appears to be independent from the type of kidney disease. Its aetiopathology is unknown and presently no standard therapy exists. We report a patient with systemic lupus erythematosus (SLE) and glomerulonephritis who developed diffuse indurated erythematous plaques covering nearly the entire legs and trunk. She had never received dialysis. The second patient suffered from SLE and antiphospholipid syndrome related thrombotic glomerulopathy. After 10 weeks of haemodialysis she developed the same skin condition. To the best of our knowledge, these are the first reports of NFD occurring in patients with SLE.
G Obermoser; M Emberger; M Wieser; B Zelger
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Lupus     Volume:  13     ISSN:  0961-2033     ISO Abbreviation:  Lupus     Publication Date:  2004  
Date Detail:
Created Date:  2004-10-06     Completed Date:  2004-11-02     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9204265     Medline TA:  Lupus     Country:  England    
Other Details:
Languages:  eng     Pagination:  609-12     Citation Subset:  IM    
Department of Dermatology, University Hospital of Innsbruck, Innsbruck, Austria.
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MeSH Terms
Antiphospholipid Syndrome / complications
Kidney Failure, Chronic / complications
Lupus Erythematosus, Systemic / complications*
Lupus Nephritis / complications*
Middle Aged
Skin Diseases / complications*,  pathology

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