Document Detail

Nephrogenic fibrosing dermopathy in pediatric patients.
MedLine Citation:
PMID:  14872332     Owner:  NLM     Status:  MEDLINE    
Nephrogenic fibrosing dermopathy (NFD) is a rare and recently recognized sclerosing skin disorder of unknown etiology. Reported cases have occurred in patients with chronic renal failure, with or without renal replacement therapy. All previous cases have been reported in older adult patients. We describe two pediatric patients who recently developed this condition and review the existing literature for NFD. Our patients included an 8-year-old boy on peritoneal dialysis with no prior renal transplant and a 19-year-old boy on hemodialysis with a history of previous failed renal transplants. We speculate that the recent emergence of this condition and occurrence in patients with chronic renal failure suggest an association with some newer pharmacological agent that has recently come into wide use. Since both our patients also had previously experienced large vessel thrombosis, hypercoagulable states may also be implicated.
Sima M Jain; Stanton Wesson; Ashraf Hassanein; Erica Canova; Miranda Hoy; Robert S Fennell; Vikas R Dharnidharka
Publication Detail:
Type:  Case Reports; Journal Article     Date:  2004-02-10
Journal Detail:
Title:  Pediatric nephrology (Berlin, Germany)     Volume:  19     ISSN:  0931-041X     ISO Abbreviation:  Pediatr. Nephrol.     Publication Date:  2004 Apr 
Date Detail:
Created Date:  2004-03-26     Completed Date:  2004-10-29     Revised Date:  2007-09-11    
Medline Journal Info:
Nlm Unique ID:  8708728     Medline TA:  Pediatr Nephrol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  467-70     Citation Subset:  IM    
Division of Dermatology, Department of Medicine, University of Florida College of Medicine, Gainesville, Florida, USA.
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MeSH Terms
Diagnosis, Differential
Epoxy Compounds / therapeutic use
Kidney Failure, Chronic / complications*,  drug therapy
Peritoneal Dialysis
Polyethylenes / therapeutic use
Renal Dialysis
Sclerosis / complications*,  physiopathology*
Skin Diseases / complications*,  physiopathology*
Reg. No./Substance:
0/Epoxy Compounds; 0/Polyamines; 0/Polyethylenes; 182683-00-7/sevelamer
Comment In:
Pediatr Nephrol. 2007 Sep;22(9):1395   [PMID:  17180360 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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