| Nephrogenic calcific arteriopathy. | |
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MedLine Citation:
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PMID: 22143475 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Vascular calcification in chronic kidney disease (CKD) is extremely common and contributes to significant morbidity and mortality among these patients. The pathogenesis is complex and involves multiple factors, including elevated calcium x phosphorus product as well as deficiencies in circulating or locally produced inhibitors of calcification, parathyroid hormone, hyperlipidemia and inflammation. Similarly, valvular heart calcifications as well as myocardial and pulmonary calcifications of fatal consequences can also occur, presumably related to the same pathogenetic factors (Figures 1, 2). Other forms of extraskeletal tissue calcification of nonfatal consequences but leading to incapacity can also develop in CKD patients (Figure 3). These complications may be prevented by awareness and early intervention directed towards correcting some of the aforementioned participating mechanisms. |
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Authors:
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Juan Jose Olivero; Juan Jorge Olivero; Peter Nguyen; Anna Kagan |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Methodist DeBakey cardiovascular journal Volume: 7 ISSN: 1947-6108 ISO Abbreviation: Methodist Debakey Cardiovasc J Publication Date: 2011 Nov |
Date Detail:
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Created Date: 2011-12-06 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101508600 Medline TA: Methodist Debakey Cardiovasc J Country: United States |
Other Details:
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Languages: eng Pagination: 33-6 Citation Subset: IM |
Affiliation:
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Methodist DeBakey Heart & Vascular Center, The Methodist Hospital, Houston, Texas. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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