| Nephrectomy Plus Endoscopy-Assisted Intussusception Ureterectomy for Patients with Renal Pelvic Cancer: Long-Term Oncologic Outcomes in Comparison with Nephroureterectomy Plus Bladder Cuff Removal. | |
| | |
MedLine Citation:
|
PMID: 21434766 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
Abstract Purpose: To assess long-term oncologic outcomes in patients with renal pelvic cancer who are receiving nephrectomy plus endoscopy-assisted intussusception ureterectomy. There has been no large study reporting long-term oncologic outcomes of this approach in comparison with those of conventional nephroureterectomy plus bladder cuff removal. Patients and Methods: We reviewed 181 consecutive patients with renal pelvic cancer who underwent open nephroureterectomy with complete bladder cuff removal (cuff removal group, n = 33), nephroureterectomy with incomplete cuff removal (orifice-remaining group, n = 39), and nephrectomy with intussusception ureterectomy (intussusception group, n = 109). Results: Patients in the intussusception group had larger tumor size, higher histologic grade, and more advanced pathologic stage (P = 0.005, 0.021, and 0.030, respectively), while the incidence of coexistent bladder/ureteral cancer was lower in this group (P < 0.001). The mean operative time was shorter in the intussusception group than in the cuff removal and orifice-remaining groups (201.2 ± 33.1 and 221.5 ± 47.2 min, respectively, P < 0.001). The 5-year extraurinary tract recurrence-free survival rate in the intussusception and cuff removal groups was 74.8% and 71.4%, respectively (log-rank P = 0.766), and it was lower in the orifice-remaining group compared with that in the intussusception group (P = 0.031). The 5-year urinary tract recurrence-free survival rate in the intussusception, cuff removal, and orifice-remaining groups was 76.6%, 65.0%, and 65.0%, respectively (intussusception vs cuff removal: P = 0.089). With both univariate and multivariate analyses, intussusception ureterectomy had no significant impact on urinary tract recurrence (multivariate P = 0.553, hazard ratio = 0.784). Conclusions: Nephrectomy plus endoscopy-assisted intussusception ureterectomy is an oncologically safe alternative for renal pelvic cancer patients, which is possibly associated with less patient morbidity. |
| | |
Authors:
|
Noboru Hara; Yasuo Kitamura; Toshihiro Saito; Shunji Wakatsuki; Yasunosuke Sakata; Shuichi Komatsubara |
Related Documents
:
|
7631056 - Transplantation of fetal mesencephalic tissue in parkinson's patients. 16362646 - Topiramate in the treatment of refractory chronic daily headache. an open trial. 21109486 - Somatotopic distribution of peri-rolandic spikes may predict prognosis in pediatric-ons... 21346166 - The effects of short interactive animation video information on preanesthetic anxiety, ... 10069766 - Unfractionated heparin and low-molecular-weight heparin for the initial treatment of ac... 304096 - Complications of dorsal column stimulation. |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-3-24 |
Journal Detail:
|
Title: Journal of endourology / Endourological Society Volume: - ISSN: 1557-900X ISO Abbreviation: - Publication Date: 2011 Mar |
Date Detail:
|
Created Date: 2011-3-25 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8807503 Medline TA: J Endourol Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
|
1 Department of Urology, Niigata Cancer Center Hospital , Niigata, Japan . |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Did Evolution Select a Nonrandom "Alphabet" of Amino Acids?
Next Document: The Cyclooxygenase-1 C50T Polymorphism Is Not Associated with Aspirin Responsiveness Status in Stabl...