| Neovalve construction in deep venous incompetence. | |
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MedLine Citation:
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PMID: 18945575 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVES: The purpose of this study is to assess the outcome of neovalve construction in two consecutive series of patients affected by postthrombotic syndrome and valve agenesis. The technique was modified in the second series so as to correct a cause of failure. METHODS: Between December 2000 and June 2007, 40 neovalve constructions were carried out in 36 patients (19 males, 17 females, median age 57, range, 29-82) affected by deep venous insufficiency. Thirty-two patients were affected by postthrombotic syndrome and 4 by valve agenesis. The 32 patients with postthrombotic syndrome were selected from among 76 patients with resistant ulcers classified C (6,S) E (S) A (S,D,P) P (R,RO) and the 4 patients with valve agenesis were selected from among 28 affected by resistant ulcers classified as C (6,S) E (C) A (S,D,P) P (R). The patients were subdivided into 2 groups. The first group included 19 operations performed in the period between December 2000 and December 2004, with a median follow-up of 54 months (range, 31-78). The second group included 21 patients operated on between January 2005 and June 2007, with a median follow-up of 5 months (range, 2-29). In the second group, a surgical variation was applied in order to prevent flap collapse and to maintain the continence of the neovalve. RESULTS: In the first series, ulcer healing was observed in 16 cases out of 19 (84%). Recurrent ulcers were observed in one case after 3 years. Valve competence was ascertained in 13 cases per 803 patient-months (1.6/100 patient-months). With regard to the second series, competence was achieved in all cases with a cumulative rate of 21 per 228 patient-months (9.2/100 patient-months). In the second series, the ulcer failed to heal in one case and recurred in two cases, with an intention-to-treat ulcer recurrence rate of three cases per 209 patient-months. Postoperative deep-venous thrombosis was observed in 3 patients in the first series. None was detected in the second series. The mortality rate was 0 and in neither group was pulmonary embolism detected. CONCLUSION: The modified technique applied to the second group seemed to improve valve continence results significantly. However, a longer follow-up period is required for the latter group to validate this technical enhancement. |
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Authors:
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Marzia Lugli; Sara Guerzoni; Mariano Garofalo; Gianluca Smedile; Oscar Maleti |
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Publication Detail:
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Type: Journal Article Date: 2008-10-22 |
Journal Detail:
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Title: Journal of vascular surgery Volume: 49 ISSN: 1097-6809 ISO Abbreviation: J. Vasc. Surg. Publication Date: 2009 Jan |
Date Detail:
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Created Date: 2009-01-28 Completed Date: 2009-02-19 Revised Date: 2012-10-03 |
Medline Journal Info:
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Nlm Unique ID: 8407742 Medline TA: J Vasc Surg Country: United States |
Other Details:
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Languages: eng Pagination: 156-62, 162.e1-2; discussion 162 Citation Subset: IM |
Affiliation:
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Department of Cardiac, Thoracic, and Vascular Surgery, Hesperia Hospital, Modena, Italy. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Female Follow-Up Studies Humans Male Middle Aged Phlebography Postthrombotic Syndrome / complications*, pathology, surgery Recurrence Surgically-Created Structures* / adverse effects Time Factors Treatment Outcome Ultrasonography, Doppler, Duplex Varicose Ulcer / etiology, pathology, surgery* Vascular Malformations / complications*, pathology, surgery Vascular Patency Vascular Surgical Procedures* / adverse effects Venous Insufficiency / etiology, pathology, surgery* Venous Valves / abnormalities, pathology, surgery* Wound Healing |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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